Quality of Life and Psychological Functioning in Children with PFAPA Syndrome
Background/Objectives: This study analyzes the impact of PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and adenitis) on health-related quality of life (HRQoL) and the psychological functioning of children and adolescents aged 2 to 1 years. Methods: A cross-sectional descriptive s...
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| Format: | Article |
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MDPI AG
2025-04-01
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| Series: | Pediatric Reports |
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| author | Xosé Ramón García-Soto Maria Isabel Villanueva-Alameda Jessica Fernández-Solana Jerónimo J. González-Bernal Arancha Bernal-Jiménez Lara Santos-Martín Juan García-Mellado Sara Calvo-Simal Rodrigo Vélez-Santamaría |
| author_facet | Xosé Ramón García-Soto Maria Isabel Villanueva-Alameda Jessica Fernández-Solana Jerónimo J. González-Bernal Arancha Bernal-Jiménez Lara Santos-Martín Juan García-Mellado Sara Calvo-Simal Rodrigo Vélez-Santamaría |
| author_sort | Xosé Ramón García-Soto |
| collection | DOAJ |
| description | Background/Objectives: This study analyzes the impact of PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and adenitis) on health-related quality of life (HRQoL) and the psychological functioning of children and adolescents aged 2 to 1 years. Methods: A cross-sectional descriptive study was conducted with 62 participants (31 males and 31 females) diagnosed with PFAPA. The Strengths and Difficulties Questionnaire (SDQ) and the Family Impact Module scale of Pediatric Quality of Life Inventory (PedsQL) were used to assess psychological functioning and HRQoL, respectively. Results: Participants exhibited predominantly low HRQoL, particularly in physical health and emotional functioning. School functioning was also affected. However, social functioning and family relationships showed more favorable scores. A positive correlation was observed between age and emotional symptoms. Family concern was the most significantly impacted aspect. Conclusions: PFAPA syndrome has a significant impact on the HRQoL of affected children and adolescents, particularly in physical and emotional aspects. A holistic approach is necessary for disease management, considering not only physical symptoms but also psychosocial and academic factors, as well as the impact on the family. |
| format | Article |
| id | doaj-art-b51a2fba78974c7db91d9b9d83d86863 |
| institution | Kabale University |
| issn | 2036-7503 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pediatric Reports |
| spelling | doaj-art-b51a2fba78974c7db91d9b9d83d868632025-08-20T03:27:21ZengMDPI AGPediatric Reports2036-75032025-04-011735110.3390/pediatric17030051Quality of Life and Psychological Functioning in Children with PFAPA SyndromeXosé Ramón García-Soto0Maria Isabel Villanueva-Alameda1Jessica Fernández-Solana2Jerónimo J. González-Bernal3Arancha Bernal-Jiménez4Lara Santos-Martín5Juan García-Mellado6Sara Calvo-Simal7Rodrigo Vélez-Santamaría8Clinical Psychology, University Hospital of Burgos, 09006 Burgos, SpainClinical Psychology, University Hospital of Burgos, 09006 Burgos, SpainDepartment of Health Sciences, University of Burgos, 09001 Burgos, SpainDepartment of Health Sciences, University of Burgos, 09001 Burgos, SpainClinical Psychology, University Hospital of Burgos, 09006 Burgos, SpainClinical Psychology, University Hospital of Burgos, 09006 Burgos, SpainPsychiatry Service, University Hospital of Burgos, 09006 Burgos, SpainResearch Unit, University Hospital of Burgos, 09006 Burgos, SpainDepartment of Health Sciences, University of Burgos, 09001 Burgos, SpainBackground/Objectives: This study analyzes the impact of PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and adenitis) on health-related quality of life (HRQoL) and the psychological functioning of children and adolescents aged 2 to 1 years. Methods: A cross-sectional descriptive study was conducted with 62 participants (31 males and 31 females) diagnosed with PFAPA. The Strengths and Difficulties Questionnaire (SDQ) and the Family Impact Module scale of Pediatric Quality of Life Inventory (PedsQL) were used to assess psychological functioning and HRQoL, respectively. Results: Participants exhibited predominantly low HRQoL, particularly in physical health and emotional functioning. School functioning was also affected. However, social functioning and family relationships showed more favorable scores. A positive correlation was observed between age and emotional symptoms. Family concern was the most significantly impacted aspect. Conclusions: PFAPA syndrome has a significant impact on the HRQoL of affected children and adolescents, particularly in physical and emotional aspects. A holistic approach is necessary for disease management, considering not only physical symptoms but also psychosocial and academic factors, as well as the impact on the family.https://www.mdpi.com/2036-7503/17/3/51PFAPAquality of lifepsychological functioningpediatricsautoinflammatory diseaseschildren’s mental health |
| spellingShingle | Xosé Ramón García-Soto Maria Isabel Villanueva-Alameda Jessica Fernández-Solana Jerónimo J. González-Bernal Arancha Bernal-Jiménez Lara Santos-Martín Juan García-Mellado Sara Calvo-Simal Rodrigo Vélez-Santamaría Quality of Life and Psychological Functioning in Children with PFAPA Syndrome Pediatric Reports PFAPA quality of life psychological functioning pediatrics autoinflammatory diseases children’s mental health |
| title | Quality of Life and Psychological Functioning in Children with PFAPA Syndrome |
| title_full | Quality of Life and Psychological Functioning in Children with PFAPA Syndrome |
| title_fullStr | Quality of Life and Psychological Functioning in Children with PFAPA Syndrome |
| title_full_unstemmed | Quality of Life and Psychological Functioning in Children with PFAPA Syndrome |
| title_short | Quality of Life and Psychological Functioning in Children with PFAPA Syndrome |
| title_sort | quality of life and psychological functioning in children with pfapa syndrome |
| topic | PFAPA quality of life psychological functioning pediatrics autoinflammatory diseases children’s mental health |
| url | https://www.mdpi.com/2036-7503/17/3/51 |
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