Development and validation of a prognostic model based on m6A-related lncRNAs to predict prognosis for papillary renal cell cancer patients

Development and validation of a prognostic model based on m6A-related lncRNAs to predict prognosis for papillary renal cell cancer patients

Abstract To evaluate the predictive utility of N6-methyladenosine (m6A)-associated long non-coding RNAs (lncRNAs) for the prognosis and immunotherapy response in papillary renal cell carcinoma (pRCC). Transcriptomic data of pRCC samples were extracted from the TCGA database. The m6A-related lncRNAs...

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Main Authors: Xianlu Zhang, Jiyuan Hu, Haoyuan Zheng, Jiayi Ren, Siyu Mu, Yiming Chen, Guoli Song, Ya-ang Chen, Gejun Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
M6A (N6-methyladenosine)
Long non-coding RNA (lncRNA)
Papillary renal cancer (pRCC)
Tumor mutation burden (TMB)
Immune cell infiltration
Prognostic model
Online Access:https://doi.org/10.1038/s41598-024-83263-0
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https://doi.org/10.1038/s41598-024-83263-0

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