Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats
Burns not only damage skin locally but generally affect the body system and have been related as the secondary cause of death. Burns can be effectively treated with a topical drug to prevent chronic inflammation. Burn wound healing is really important for ensuring overall health and well-being. This...
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Universitas Airlangga, Faculty of Veterinary Medicine
2023-12-01
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| Series: | Jurnal Medik Veteriner |
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| Online Access: | https://e-journal.unair.ac.id/JMV/article/view/46258 |
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| author | Rosenna Tiara Panggabean Sri Agus Sudjarwo Anwar Ma’ruf Thomas Valentinus Widiyatno Ira Sari Yudaniayanti Rochmah Kurnijasanti Aswin Rafif Khairullah |
| author_facet | Rosenna Tiara Panggabean Sri Agus Sudjarwo Anwar Ma’ruf Thomas Valentinus Widiyatno Ira Sari Yudaniayanti Rochmah Kurnijasanti Aswin Rafif Khairullah |
| author_sort | Rosenna Tiara Panggabean |
| collection | DOAJ |
| description | Burns not only damage skin locally but generally affect the body system and have been related as the secondary cause of death. Burns can be effectively treated with a topical drug to prevent chronic inflammation. Burn wound healing is really important for ensuring overall health and well-being. This study aimed to determine the effect of Sauropus androgynous leaves extract gel on the number of fibroblasts, fibrocytes, and collagen density on burn wound healing in albino rats. A total of 50 male albino rats were randomly divided into five groups i.e. (C-) was normal skin, (C+) was skin burn treated with placebo, (T1) was skin burn treated with 2.5% of S. androgynous leaves extract gel, (T2) was skin burn treated with 5% of S. androgynous leaves extract gel, and (T3) was skin burn treated with 10% of S. androgynous leaves extract the gel. The amount of 25 albino rats’ skin samples were collected on the 8th day, and the remaining samples were collected on the 15th day. The results showed that 10% of S. androgynous leaves extract gel improved faster, as indicated by the increased number of fibroblasts, fibrocytes, and collagen density. This study can be concluded that 10% of S. androgynous leaves extract gel was the effective dosage to increase the number of fibroblasts, fibrocytes, and collagen density in burn wound healing. |
| format | Article |
| id | doaj-art-b43c859f1e2149e984a86361b6c758b9 |
| institution | Kabale University |
| issn | 2615-7497 2581-012X |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Universitas Airlangga, Faculty of Veterinary Medicine |
| record_format | Article |
| series | Jurnal Medik Veteriner |
| spelling | doaj-art-b43c859f1e2149e984a86361b6c758b92025-01-03T01:49:51ZengUniversitas Airlangga, Faculty of Veterinary MedicineJurnal Medik Veteriner2615-74972581-012X2023-12-016310711510.20473/jmv.vol6.iss3.2023.107-11544344Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino RatsRosenna Tiara Panggabean0https://orcid.org/0009-0007-4321-9028Sri Agus Sudjarwo1https://orcid.org/0000-0002-5184-2377Anwar Ma’ruf2https://orcid.org/0000-0001-7158-9156Thomas Valentinus Widiyatno3https://orcid.org/0000-0002-0745-3796Ira Sari Yudaniayanti4https://orcid.org/0000-0003-2994-3208Rochmah Kurnijasanti5https://orcid.org/0000-0002-7069-6205Aswin Rafif Khairullah6https://orcid.org/0000-0001-9421-9342Bachelor Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, SurabayaDepartment of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, SurabayaDepartment of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, SurabayaDepartment of Veterinary Pathology, Faculty of Veterinary Medicine, Universitas Airlangga, SurabayaDepartment of Veterinary Clinic, Faculty of Veterinary Medicine, Universitas Airlangga, SurabayaDepartment of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, SurabayaDoctoral Program of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, SurabayaBurns not only damage skin locally but generally affect the body system and have been related as the secondary cause of death. Burns can be effectively treated with a topical drug to prevent chronic inflammation. Burn wound healing is really important for ensuring overall health and well-being. This study aimed to determine the effect of Sauropus androgynous leaves extract gel on the number of fibroblasts, fibrocytes, and collagen density on burn wound healing in albino rats. A total of 50 male albino rats were randomly divided into five groups i.e. (C-) was normal skin, (C+) was skin burn treated with placebo, (T1) was skin burn treated with 2.5% of S. androgynous leaves extract gel, (T2) was skin burn treated with 5% of S. androgynous leaves extract gel, and (T3) was skin burn treated with 10% of S. androgynous leaves extract the gel. The amount of 25 albino rats’ skin samples were collected on the 8th day, and the remaining samples were collected on the 15th day. The results showed that 10% of S. androgynous leaves extract gel improved faster, as indicated by the increased number of fibroblasts, fibrocytes, and collagen density. This study can be concluded that 10% of S. androgynous leaves extract gel was the effective dosage to increase the number of fibroblasts, fibrocytes, and collagen density in burn wound healing.https://e-journal.unair.ac.id/JMV/article/view/46258collagenfibroblastfibrocytehealthsauropus androgynous |
| spellingShingle | Rosenna Tiara Panggabean Sri Agus Sudjarwo Anwar Ma’ruf Thomas Valentinus Widiyatno Ira Sari Yudaniayanti Rochmah Kurnijasanti Aswin Rafif Khairullah Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats Jurnal Medik Veteriner collagen fibroblast fibrocyte health sauropus androgynous |
| title | Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats |
| title_full | Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats |
| title_fullStr | Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats |
| title_full_unstemmed | Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats |
| title_short | Efficacy of Sauropus androgynous Leaves Extract Gel on Burn Wound Healing in Albino Rats |
| title_sort | efficacy of sauropus androgynous leaves extract gel on burn wound healing in albino rats |
| topic | collagen fibroblast fibrocyte health sauropus androgynous |
| url | https://e-journal.unair.ac.id/JMV/article/view/46258 |
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