Striatal Cholinergic Interneurons Control Physical Nicotine Withdrawal via Muscarinic Receptor Signaling

Striatal Cholinergic Interneurons Control Physical Nicotine Withdrawal via Muscarinic Receptor Signaling

Abstract Striatal cholinergic interneurons (ChIs) provide acetylcholine tone to the striatum and govern motor functions. Nicotine withdrawal elicits physical symptoms that dysregulate motor behavior. Here, the role of striatal ChIs in physical nicotine withdrawal is investigated. Mice under RNAi‐dep...

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Bibliographic Details
Main Authors: Baeksun Kim, Han Ah Kim, Junsung Woo, Hyeon‐Jeong Lee, Tae Kyoo Kim, Hophil Min, C. Justin Lee, Heh‐In Im
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
cholinergic interneurons
dopamine
dorsal striatum
muscarinic receptor
neural activity
nicotine withdrawal
Online Access:https://doi.org/10.1002/advs.202402274
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https://doi.org/10.1002/advs.202402274

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