Signalling pathways and cellular functions of KDEL receptors: implications in cancer biology

Abstract KDEL receptors (KDELRs) are a small family of seven-transmembrane domain proteins primarily localized to the membranes of the Golgi apparatus and endoplasmic reticulum (ER). These receptors are responsible for retrieving ER-resident chaperones that have trafficked to post-ER compartments. B...

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Bibliographic Details
Main Authors: Beatrice Dufrusine, Ilaria Cela, Chiara Gramegna Tota, Marta Palumbo, Michele Sallese
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Cellular and Molecular Life Sciences
Online Access:https://doi.org/10.1007/s00018-025-05820-8
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