Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis

Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis

Abstract Background: Clear cell renal cell carcinoma (ccRCC) has a high incidence rate and poor prognosis, and currently lacks effective therapies. Recently, peptide-based drugs have shown promise in cancer treatment. In this research, a new endogenous peptide called CBDP1 was discovered in ccRCC an...

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Bibliographic Details
Main Authors: Yang Zhang, Wei Zhu, Ruijie Tao, Weijian Li, Chunming Jiang, Xiang Yan
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
Clear cell renal cell carcinoma
Endogenous peptide
YTHDF2
TRPM3
USP5
Online Access:https://doi.org/10.1186/s12967-025-06091-4
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