Molecular Mechanisms and Genome-Wide Aspects of PPAR Subtype Specific Transactivation
The peroxisome proliferator-activated receptors (PPARs) are central regulators of fat metabolism, energy homeostasis, proliferation, and inflammation. The three PPAR subtypes, PPAR𝛼, 𝛽/𝛿, and 𝛾 activate overlapping but also very different target gene programs. This review summarizes the insights int...
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Main Authors: | Anne Bugge, Susanne Mandrup |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2010/169506 |
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