Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract Disease

Obstructive feline lower urinary tract disease (OFLUTD) is the most common complication of the urinary system, as metabolic and electrolyte changes can alter the functioning of the autonomic nervous system (ANS). The objective of this study was to describe the indices of heart rate variability (HRV)...

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Main Authors: Mary Marlene Tarazona Molina, Priscylla Tatiana Chalfun Guimarães-Okamoto, Amanda Sarita Cruz-Aleixo, Miriam Harumi Tsunemi, Jaqueline Valença Corrêa, Jessica Cardia de Melo, Luiz Henrique de Araújo Machado, Maria Lucia Gomes Lourenço
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/14/23/3479
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author Mary Marlene Tarazona Molina
Priscylla Tatiana Chalfun Guimarães-Okamoto
Amanda Sarita Cruz-Aleixo
Miriam Harumi Tsunemi
Jaqueline Valença Corrêa
Jessica Cardia de Melo
Luiz Henrique de Araújo Machado
Maria Lucia Gomes Lourenço
author_facet Mary Marlene Tarazona Molina
Priscylla Tatiana Chalfun Guimarães-Okamoto
Amanda Sarita Cruz-Aleixo
Miriam Harumi Tsunemi
Jaqueline Valença Corrêa
Jessica Cardia de Melo
Luiz Henrique de Araújo Machado
Maria Lucia Gomes Lourenço
author_sort Mary Marlene Tarazona Molina
collection DOAJ
description Obstructive feline lower urinary tract disease (OFLUTD) is the most common complication of the urinary system, as metabolic and electrolyte changes can alter the functioning of the autonomic nervous system (ANS). The objective of this study was to describe the indices of heart rate variability (HRV) and their correlations with the observed alterations in Systolic Blood Pressure (SBP) and electrocardiographic, biochemical, and haemogasometric indices in cats diagnosed with OFLUTD. Sixty-five male cats up to 10 years of age were divided into two groups. The control group (CG) was composed of 25 healthy cats, and the obstructed group (OG) consisted of 40 cats with OFLUTD. The OG was evaluated by electrocardiography and blood pressure at four different time points. In the CG, electrocardiographic evaluation and SBP measurement were performed. A comparison of the HRV between the CG and OG (M0) revealed differences in the SDNN (standard deviation of all normal RR-NN) parameters (sympathetic and parasympathetic tone) and in the rMSSD (parasympathetic tone); there was a difference in the SBP, which was greater in the CG. There were higher rates in the CG. The HF and HR were greater in OG. The HRV serves as a preventive tool and predicts the severity of OFLUTD in patients due to an imbalance in the ANS.
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institution Kabale University
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publishDate 2024-12-01
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spelling doaj-art-b3c3ce87582e4f449b0adf7c1d15f62e2024-12-13T16:21:22ZengMDPI AGAnimals2076-26152024-12-011423347910.3390/ani14233479Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract DiseaseMary Marlene Tarazona Molina0Priscylla Tatiana Chalfun Guimarães-Okamoto1Amanda Sarita Cruz-Aleixo2Miriam Harumi Tsunemi3Jaqueline Valença Corrêa4Jessica Cardia de Melo5Luiz Henrique de Araújo Machado6Maria Lucia Gomes Lourenço7Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618970, BrazilDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618970, BrazilDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618970, BrazilInstitute of Biosciences, São Paulo State University (UNESP), Botucatu 18618689, BrazilDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618970, BrazilDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618970, BrazilDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618970, BrazilDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618970, BrazilObstructive feline lower urinary tract disease (OFLUTD) is the most common complication of the urinary system, as metabolic and electrolyte changes can alter the functioning of the autonomic nervous system (ANS). The objective of this study was to describe the indices of heart rate variability (HRV) and their correlations with the observed alterations in Systolic Blood Pressure (SBP) and electrocardiographic, biochemical, and haemogasometric indices in cats diagnosed with OFLUTD. Sixty-five male cats up to 10 years of age were divided into two groups. The control group (CG) was composed of 25 healthy cats, and the obstructed group (OG) consisted of 40 cats with OFLUTD. The OG was evaluated by electrocardiography and blood pressure at four different time points. In the CG, electrocardiographic evaluation and SBP measurement were performed. A comparison of the HRV between the CG and OG (M0) revealed differences in the SDNN (standard deviation of all normal RR-NN) parameters (sympathetic and parasympathetic tone) and in the rMSSD (parasympathetic tone); there was a difference in the SBP, which was greater in the CG. There were higher rates in the CG. The HF and HR were greater in OG. The HRV serves as a preventive tool and predicts the severity of OFLUTD in patients due to an imbalance in the ANS.https://www.mdpi.com/2076-2615/14/23/3479autonomic nervous systemobstructioncardiologypotassium
spellingShingle Mary Marlene Tarazona Molina
Priscylla Tatiana Chalfun Guimarães-Okamoto
Amanda Sarita Cruz-Aleixo
Miriam Harumi Tsunemi
Jaqueline Valença Corrêa
Jessica Cardia de Melo
Luiz Henrique de Araújo Machado
Maria Lucia Gomes Lourenço
Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract Disease
Animals
autonomic nervous system
obstruction
cardiology
potassium
title Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract Disease
title_full Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract Disease
title_fullStr Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract Disease
title_full_unstemmed Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract Disease
title_short Cardiac Autonomic Modulation in Domestic Cats with Obstructive Lower Urinary Tract Disease
title_sort cardiac autonomic modulation in domestic cats with obstructive lower urinary tract disease
topic autonomic nervous system
obstruction
cardiology
potassium
url https://www.mdpi.com/2076-2615/14/23/3479
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