Nutlin-3 promotes HBV replication by activating mTOR-mediated autophagy

Nutlin-3 promotes HBV replication by activating mTOR-mediated autophagy

BackgroundCurrently, there are approximately 240 million individuals worldwide suffering from chronic hepatitis B infection, yet a definitive cure remains elusive. In the context of pharmaceutical interventions for this patient population, the potential issue of Hepatitis B virus (HBV) reactivation...

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Bibliographic Details
Main Authors: Shaowei Han, Yuanyuan Li, Junnan Wang, Yong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Acta Virologica
Subjects:
Nutlin-3
HBV
mTOR
autophagy
p53
Online Access:https://www.frontierspartnerships.org/articles/10.3389/av.2024.12585/full
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