Local Administration of (−)-Epigallocatechin-3-Gallate as a Local Anesthetic Agent Inhibits the Excitability of Rat Nociceptive Primary Sensory Neurons

Local Administration of (−)-Epigallocatechin-3-Gallate as a Local Anesthetic Agent Inhibits the Excitability of Rat Nociceptive Primary Sensory Neurons

While the impact of (−)-epigallocatechin-3-gallate (EGCG) on modulating nociceptive secondary neuron activity has been documented, it is still unknown how EGCG affects the excitability of nociceptive primary neurons in vivo. The objective of the current study was to investigate whether administering...

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Bibliographic Details
Main Authors: Syogo Utugi, Risako Chida, Sana Yamaguchi, Yukito Sashide, Mamoru Takeda
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
alternative medicine
extracellular single unit recording
lidocaine
(−)-epigallocatechin-3-gallate
trigeminal pain
primary afferent
Online Access:https://www.mdpi.com/2073-4409/14/1/52
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