Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation Genes
The present study aimed to investigate whether supplementation of modified lysophospholipids (LPLs) in the diet of broiler breeders can benefit their offspring. A total of 264 49-week-old breeders (Ross 308) were allocated and fed based on a 2 × 2 factorial arrangement with two levels of dietary ene...
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2024-10-01
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| author | Mohammad Sedghi Fatemeh Javanmard Anvar Amoozmehr Saeid Zamany Ishmael Mohammadi Woo Kim Venkata Sesha Reddy Choppa |
| author_facet | Mohammad Sedghi Fatemeh Javanmard Anvar Amoozmehr Saeid Zamany Ishmael Mohammadi Woo Kim Venkata Sesha Reddy Choppa |
| author_sort | Mohammad Sedghi |
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| description | The present study aimed to investigate whether supplementation of modified lysophospholipids (LPLs) in the diet of broiler breeders can benefit their offspring. A total of 264 49-week-old breeders (Ross 308) were allocated and fed based on a 2 × 2 factorial arrangement with two levels of dietary energy (normal energy = 2800 kcal/kg and low energy = 2760 kcal/kg) and two LPL levels (0 and 0.5 g/kg) for periods of 8 and 12 weeks. The offspring were assessed for growth performance, serum parameters, hepatic antioxidative capability, and expression of genes involved in liver β-oxidation at 7 days old. The LPL inclusion improved (<i>p</i> < 0.01) average body weight (ABW), average daily gain (ADG), and feed conversion ratio (FCR). The offspring of 61-week-old breeders fed with LPL exhibited reduced serum triglyceride levels (<i>p</i> < 0.01) but an increase in hepatic glutathione peroxidase (<i>p</i> < 0.05). The LPL increased (<i>p</i> < 0.001) the mRNA expression of the <i>PGC-1α</i> gene in the liver. Supplementing LPL in low-energy diets resulted in higher <i>FABP1</i> gene expression (<i>p</i> < 0.05) in the intestine. In conclusion, LPL supplementation in the breeders’ diet improved offspring performance by enhancing fatty acid absorption, hepatic indices, and the expression of genes involved in liver β-oxidation. |
| format | Article |
| id | doaj-art-b360bdc819074a20b9778dd76633c2ea |
| institution | Kabale University |
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| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj-art-b360bdc819074a20b9778dd76633c2ea2024-11-08T14:32:24ZengMDPI AGAnimals2076-26152024-10-011421306610.3390/ani14213066Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation GenesMohammad Sedghi0Fatemeh Javanmard1Anvar Amoozmehr2Saeid Zamany3Ishmael Mohammadi4Woo Kim5Venkata Sesha Reddy Choppa6Department of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, IranDepartment of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, IranDepartment of Animal and Poultry Nutrition, Faculty of Animal Science, Gorgan University of Agricultural Sciences and Natural Resources, Shahid Beheshti Ave, Gorgan 49138-15739, IranDepartment of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, IranDepartment of Animal Sciences, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, IranDepartment of Poultry Science, University of Georgia, Athens, GA 30602, USADepartment of Poultry Science, University of Georgia, Athens, GA 30602, USAThe present study aimed to investigate whether supplementation of modified lysophospholipids (LPLs) in the diet of broiler breeders can benefit their offspring. A total of 264 49-week-old breeders (Ross 308) were allocated and fed based on a 2 × 2 factorial arrangement with two levels of dietary energy (normal energy = 2800 kcal/kg and low energy = 2760 kcal/kg) and two LPL levels (0 and 0.5 g/kg) for periods of 8 and 12 weeks. The offspring were assessed for growth performance, serum parameters, hepatic antioxidative capability, and expression of genes involved in liver β-oxidation at 7 days old. The LPL inclusion improved (<i>p</i> < 0.01) average body weight (ABW), average daily gain (ADG), and feed conversion ratio (FCR). The offspring of 61-week-old breeders fed with LPL exhibited reduced serum triglyceride levels (<i>p</i> < 0.01) but an increase in hepatic glutathione peroxidase (<i>p</i> < 0.05). The LPL increased (<i>p</i> < 0.001) the mRNA expression of the <i>PGC-1α</i> gene in the liver. Supplementing LPL in low-energy diets resulted in higher <i>FABP1</i> gene expression (<i>p</i> < 0.05) in the intestine. In conclusion, LPL supplementation in the breeders’ diet improved offspring performance by enhancing fatty acid absorption, hepatic indices, and the expression of genes involved in liver β-oxidation.https://www.mdpi.com/2076-2615/14/21/3066lysophospholipidmetabolizable energyhepatic β-oxidation<i>PGC-1α</i><i>LPCAT3</i>gene expression |
| spellingShingle | Mohammad Sedghi Fatemeh Javanmard Anvar Amoozmehr Saeid Zamany Ishmael Mohammadi Woo Kim Venkata Sesha Reddy Choppa Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation Genes Animals lysophospholipid metabolizable energy hepatic β-oxidation <i>PGC-1α</i> <i>LPCAT3</i> gene expression |
| title | Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation Genes |
| title_full | Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation Genes |
| title_fullStr | Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation Genes |
| title_full_unstemmed | Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation Genes |
| title_short | Lysophospholipid Supplementation in Broiler Breeders’ Diet Benefits Offspring’s Productive Performance, Blood Parameters, and Hepatic β-Oxidation Genes |
| title_sort | lysophospholipid supplementation in broiler breeders diet benefits offspring s productive performance blood parameters and hepatic β oxidation genes |
| topic | lysophospholipid metabolizable energy hepatic β-oxidation <i>PGC-1α</i> <i>LPCAT3</i> gene expression |
| url | https://www.mdpi.com/2076-2615/14/21/3066 |
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