Exosomes loaded with the anti-cancer molecule mir-1-3p inhibit intrapulmonary colonization and growth of human esophageal squamous carcinoma cells

Exosomes loaded with the anti-cancer molecule mir-1-3p inhibit intrapulmonary colonization and growth of human esophageal squamous carcinoma cells

Abstract Background The overall prognosis of patients with esophageal cancer (EC) is extremely poor. There is an urgent need to develop innovative therapeutic strategies. This study will investigate the anti-cancer effects of exosomes loaded with specific anti-cancer microRNAs in vivo and in vitro....

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Bibliographic Details
Main Authors: Yanmei Yu, Bingjie Jin, Ruzhen Jia, Lei Shi, Yong Chen, Jian Ge, Changqin Xu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
Esophageal squamous carcinoma
MicroRNA
Exosomes
Gene therapy
Nanocarriers
Online Access:https://doi.org/10.1186/s12967-024-05997-9
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