High rheumatoid factor does not diminish efficacy of TNF inhibitors in seropositive JIA
Abstract Objectives Rheumatoid factor (RF) binds to the immunoglobulin Fc portion, which might influence the efficacy of Fc-carrying TNF inhibitors (TNFi). This has been shown in studies in adults with RF-positive RA, but not yet in children. The aim of this study was to determine efficacy of TNFi i...
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| Main Authors: | Boris Hügle, Gerd Horneff, Johannes-Peter Haas |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
|
| Series: | Pediatric Rheumatology Online Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12969-025-01125-z |
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