Intratumor microbiome-derived butyrate promotes chemo-resistance in colorectal cancer

Intratumor microbiome-derived butyrate promotes chemo-resistance in colorectal cancer

IntroductionColorectal cancer (CRC) is a leading cause of cancer-related mortality globally. Although tumor immunotherapy is widely recognized for treating unresectable CRC, challenges such as ineffective immunotherapy and drug resistance remain prevalent. While intratumor microbiome-derived butyrat...

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Bibliographic Details
Main Authors:	Linsheng Xu, Bingde Hu, Jingli He, Xin Fu, Na Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Series:	Frontiers in Pharmacology
Subjects:	colorectal cancer chemoresistance microbiome butyrate biomarkers
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1510851/full
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