Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察)
Objective To investigate the effect of predictive nursing strategies on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome. Methods Totally 40 patients undergoing subcutaneous injection therapy with azacitidine for high-risk myelodysplastic syndrome were ran...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Journal of International Translational Medicine Limited
2022-07-01
|
| Series: | 中西医结合护理 |
| Subjects: | |
| Online Access: | http://www.zxyjhhl.hk/thesisDetails#10.55111/j.issn2709-1961.202205105 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841564035522232320 |
|---|---|
| author | WANG Xue (王雪) CAO Hongjing (曹红京) LI Ning (李宁) CHEN Siyu (陈思雨) REN Lixin (任利鑫) SONG Meijia (宋美佳) |
| author_facet | WANG Xue (王雪) CAO Hongjing (曹红京) LI Ning (李宁) CHEN Siyu (陈思雨) REN Lixin (任利鑫) SONG Meijia (宋美佳) |
| author_sort | WANG Xue (王雪) |
| collection | DOAJ |
| description | Objective To investigate the effect of predictive nursing strategies on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome. Methods Totally 40 patients undergoing subcutaneous injection therapy with azacitidine for high-risk myelodysplastic syndrome were randomly divided into the observation group and control group, with 20 cases in each group. Routing nursing management including posture nursing, oral care, psychological care and nursing of adverse reactions was carried out in the control group. In the observation group, a special nursing team was set up to enhance the predictive nursing interventions such as nutrition support, prevention of infection and hemorrhage, and so on. The side effects of azacitidine therapy were observed analyzed. Results The incidence of adverse reactions in the observation group was significantly lower than that in the control group (10. 00% vs. 45. 00%, P＜0. 05). Conclusion For those patients undergoing subcutaneous injection therapy with azacitidine for high-risk myelodysplastic syndrome, the predictive nursing is potentially effective to reduce the incidence of adverse drug reactions. (目的 探讨预见性护理干预预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的效果。方法 40例较高危骨髓增生异常综合征患者随机分为观察组(n=20)和对照组(n=20)。两组患者均给予阿扎胞苷皮下注射治疗。对照组实施常规护理, 包括体位护理、口腔护理、心理护理和不良反应护理; 观察组实施预见性护理干预, 成立预见性护理小组, 强化营养干预、感染预防、出血预防等护理措施。比较两组不良反应发生情况。结果 观察组不良反应发生率10. 00%(2/20), 低于对照组的45. 00%(9/20), 差异有统计学意义(P＜0. 05)。结论 对较高危骨髓增生异常综合征患者, 应用阿扎胞苷治疗的同时配合预见性护理, 可以有效降低不良反应的发生风险。) |
| format | Article |
| id | doaj-art-b2b57ed6c3a44a9b9db0fcd3d79b4fcc |
| institution | Kabale University |
| issn | 2709-1961 |
| language | zho |
| publishDate | 2022-07-01 |
| publisher | Journal of International Translational Medicine Limited |
| record_format | Article |
| series | 中西医结合护理 |
| spelling | doaj-art-b2b57ed6c3a44a9b9db0fcd3d79b4fcc2025-01-02T23:18:05ZzhoJournal of International Translational Medicine Limited中西医结合护理2709-19612022-07-0187151910.55111/j.issn2709-1961.202205105T202205105Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察)WANG Xue (王雪)0CAO Hongjing (曹红京)1LI Ning (李宁)2CHEN Siyu (陈思雨)3REN Lixin (任利鑫)4SONG Meijia (宋美佳)5Department of Hematology, Beijing Longfu Hospital, Beijing, 100010 (北京市隆福医院 血液科, 北京, 100010)Department of Nursing, Beijing Longfu Hospital, Beijing, 100010 (北京市隆福医院 护理部, 北京, 100010)Department of Nursing, Beijing Longfu Hospital, Beijing, 100010 (北京市隆福医院 护理部, 北京, 100010)Department of Hematology, Beijing Longfu Hospital, Beijing, 100010 (北京市隆福医院 血液科, 北京, 100010)Department of Hematology, Beijing Longfu Hospital, Beijing, 100010 (北京市隆福医院 血液科, 北京, 100010)Department of Hematology, Beijing Longfu Hospital, Beijing, 100010 (北京市隆福医院 血液科, 北京, 100010)Objective To investigate the effect of predictive nursing strategies on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome. Methods Totally 40 patients undergoing subcutaneous injection therapy with azacitidine for high-risk myelodysplastic syndrome were randomly divided into the observation group and control group, with 20 cases in each group. Routing nursing management including posture nursing, oral care, psychological care and nursing of adverse reactions was carried out in the control group. In the observation group, a special nursing team was set up to enhance the predictive nursing interventions such as nutrition support, prevention of infection and hemorrhage, and so on. The side effects of azacitidine therapy were observed analyzed. Results The incidence of adverse reactions in the observation group was significantly lower than that in the control group (10. 00% vs. 45. 00%, P＜0. 05). Conclusion For those patients undergoing subcutaneous injection therapy with azacitidine for high-risk myelodysplastic syndrome, the predictive nursing is potentially effective to reduce the incidence of adverse drug reactions. (目的 探讨预见性护理干预预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的效果。方法 40例较高危骨髓增生异常综合征患者随机分为观察组(n=20)和对照组(n=20)。两组患者均给予阿扎胞苷皮下注射治疗。对照组实施常规护理, 包括体位护理、口腔护理、心理护理和不良反应护理; 观察组实施预见性护理干预, 成立预见性护理小组, 强化营养干预、感染预防、出血预防等护理措施。比较两组不良反应发生情况。结果 观察组不良反应发生率10. 00%(2/20), 低于对照组的45. 00%(9/20), 差异有统计学意义(P＜0. 05)。结论 对较高危骨髓增生异常综合征患者, 应用阿扎胞苷治疗的同时配合预见性护理, 可以有效降低不良反应的发生风险。)http://www.zxyjhhl.hk/thesisDetails#10.55111/j.issn2709-1961.202205105azacitidinehigh-risk myelodysplastic syndromeside effectspsychological careinfectionhemorrhage阿扎胞苷较高危骨髓增生异常综合征不良反应心理护理感染出血 |
| spellingShingle | WANG Xue (王雪) CAO Hongjing (曹红京) LI Ning (李宁) CHEN Siyu (陈思雨) REN Lixin (任利鑫) SONG Meijia (宋美佳) Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察) 中西医结合护理 azacitidine high-risk myelodysplastic syndrome side effects psychological care infection hemorrhage 阿扎胞苷 较高危骨髓增生异常综合征 不良反应 心理护理 感染 出血 |
| title | Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察) |
| title_full | Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察) |
| title_fullStr | Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察) |
| title_full_unstemmed | Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察) |
| title_short | Effect of nursing interventions on preventing side effects of azacitidine in patients with high-risk myelodysplastic syndrome (预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察) |
| title_sort | effect of nursing interventions on preventing side effects of azacitidine in patients with high risk myelodysplastic syndrome 预防较高危骨髓增生异常综合征患者阿扎胞苷治疗所致不良反应的护理效果观察 |
| topic | azacitidine high-risk myelodysplastic syndrome side effects psychological care infection hemorrhage 阿扎胞苷 较高危骨髓增生异常综合征 不良反应 心理护理 感染 出血 |
| url | http://www.zxyjhhl.hk/thesisDetails#10.55111/j.issn2709-1961.202205105 |
| work_keys_str_mv | AT wangxuewángxuě effectofnursinginterventionsonpreventingsideeffectsofazacitidineinpatientswithhighriskmyelodysplasticsyndromeyùfángjiàogāowēigǔsuǐzēngshēngyìchángzōnghézhēnghuànzhěāzhābāogānzhìliáosuǒzhìbùliángfǎnyīngdehùlǐxiàoguǒguānchá AT caohongjingcáohóngjīng effectofnursinginterventionsonpreventingsideeffectsofazacitidineinpatientswithhighriskmyelodysplasticsyndromeyùfángjiàogāowēigǔsuǐzēngshēngyìchángzōnghézhēnghuànzhěāzhābāogānzhìliáosuǒzhìbùliángfǎnyīngdehùlǐxiàoguǒguānchá AT lininglǐníng effectofnursinginterventionsonpreventingsideeffectsofazacitidineinpatientswithhighriskmyelodysplasticsyndromeyùfángjiàogāowēigǔsuǐzēngshēngyìchángzōnghézhēnghuànzhěāzhābāogānzhìliáosuǒzhìbùliángfǎnyīngdehùlǐxiàoguǒguānchá AT chensiyuchénsīyǔ effectofnursinginterventionsonpreventingsideeffectsofazacitidineinpatientswithhighriskmyelodysplasticsyndromeyùfángjiàogāowēigǔsuǐzēngshēngyìchángzōnghézhēnghuànzhěāzhābāogānzhìliáosuǒzhìbùliángfǎnyīngdehùlǐxiàoguǒguānchá AT renlixinrènlìxīn effectofnursinginterventionsonpreventingsideeffectsofazacitidineinpatientswithhighriskmyelodysplasticsyndromeyùfángjiàogāowēigǔsuǐzēngshēngyìchángzōnghézhēnghuànzhěāzhābāogānzhìliáosuǒzhìbùliángfǎnyīngdehùlǐxiàoguǒguānchá AT songmeijiasòngměijiā effectofnursinginterventionsonpreventingsideeffectsofazacitidineinpatientswithhighriskmyelodysplasticsyndromeyùfángjiàogāowēigǔsuǐzēngshēngyìchángzōnghézhēnghuànzhěāzhābāogānzhìliáosuǒzhìbùliángfǎnyīngdehùlǐxiàoguǒguānchá |