Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatment
Objective To evaluate the complications associated with microwave ablation (MWA) in treating persistent/recurrent hyperparathyroidism (HPT) post-surgical or ablative treatments.Materials and methods From January 2015 to December 2022, 87 persistent/recurrent HPT patients (primary HPT [PHPT]: seconda...
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Taylor & Francis Group
2024-12-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/02656736.2024.2308063 |
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| author | Ying Wei Zhen-long Zhao Jie Wu Shi-liang Cao Li-li Peng Yan Li Ming-an Yu |
| author_facet | Ying Wei Zhen-long Zhao Jie Wu Shi-liang Cao Li-li Peng Yan Li Ming-an Yu |
| author_sort | Ying Wei |
| collection | DOAJ |
| description | Objective To evaluate the complications associated with microwave ablation (MWA) in treating persistent/recurrent hyperparathyroidism (HPT) post-surgical or ablative treatments.Materials and methods From January 2015 to December 2022, 87 persistent/recurrent HPT patients (primary HPT [PHPT]: secondary HPT [SHPT] = 13:74) who underwent MWA after surgical or ablative treatment were studied. Grouping was based on ablation order (initial vs. re-MWA), prior treatment (parathyroidectomy [PTX] vs. MWA), and etiology (PHPT vs. SHPT). The study focused on documenting and comparing treatment complications and analyzing major complication risk factors.Result Among the 87 patients, the overall complication rate was 17.6% (15/87), with major complications at 13.8% (12/87) and minor complications at 3.4% (3/87). Major complications included recurrent laryngeal nerve (RLN) palsy (12.6%) and Horner syndrome (1.1%), while minor complications were limited to hematoma (3.4%). Severe hypocalcemia noted in 21.6% of SHPT patients. No significant differences in major complication rates were observed between initial and re-MWA groups (10.7% vs. 13.8%, p = 0.455), PTX and MWA groups (12.5% vs. 15.4%, p = 0.770), or PHPT and SHPT groups (15.4% vs. 13.5%, p > 0.999). Risk factors for RLN palsy included ablation of superior and large parathyroid glands (>1.7 cm). All patients recovered spontaneously except for one with permanent RLN palsy in the PTX group (2.1%).Conclusion Complication rates for MWA post-surgical or ablative treatments were comparable to initial MWA rates. Most complications were transient, indicating MWA as a viable and safe treatment option for persistent/recurrent HPT patients. |
| format | Article |
| id | doaj-art-b2a2d6fb0304488b821c3ffb375806a4 |
| institution | Kabale University |
| issn | 0265-6736 1464-5157 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj-art-b2a2d6fb0304488b821c3ffb375806a42025-01-03T09:30:28ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572024-12-0141110.1080/02656736.2024.2308063Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatmentYing Wei0Zhen-long Zhao1Jie Wu2Shi-liang Cao3Li-li Peng4Yan Li5Ming-an Yu6Department of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, ChinaObjective To evaluate the complications associated with microwave ablation (MWA) in treating persistent/recurrent hyperparathyroidism (HPT) post-surgical or ablative treatments.Materials and methods From January 2015 to December 2022, 87 persistent/recurrent HPT patients (primary HPT [PHPT]: secondary HPT [SHPT] = 13:74) who underwent MWA after surgical or ablative treatment were studied. Grouping was based on ablation order (initial vs. re-MWA), prior treatment (parathyroidectomy [PTX] vs. MWA), and etiology (PHPT vs. SHPT). The study focused on documenting and comparing treatment complications and analyzing major complication risk factors.Result Among the 87 patients, the overall complication rate was 17.6% (15/87), with major complications at 13.8% (12/87) and minor complications at 3.4% (3/87). Major complications included recurrent laryngeal nerve (RLN) palsy (12.6%) and Horner syndrome (1.1%), while minor complications were limited to hematoma (3.4%). Severe hypocalcemia noted in 21.6% of SHPT patients. No significant differences in major complication rates were observed between initial and re-MWA groups (10.7% vs. 13.8%, p = 0.455), PTX and MWA groups (12.5% vs. 15.4%, p = 0.770), or PHPT and SHPT groups (15.4% vs. 13.5%, p > 0.999). Risk factors for RLN palsy included ablation of superior and large parathyroid glands (>1.7 cm). All patients recovered spontaneously except for one with permanent RLN palsy in the PTX group (2.1%).Conclusion Complication rates for MWA post-surgical or ablative treatments were comparable to initial MWA rates. Most complications were transient, indicating MWA as a viable and safe treatment option for persistent/recurrent HPT patients.https://www.tandfonline.com/doi/10.1080/02656736.2024.2308063Microwave ablationcomplicationhyperparathyroidismrecurrent laryngeal nerve |
| spellingShingle | Ying Wei Zhen-long Zhao Jie Wu Shi-liang Cao Li-li Peng Yan Li Ming-an Yu Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatment International Journal of Hyperthermia Microwave ablation complication hyperparathyroidism recurrent laryngeal nerve |
| title | Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatment |
| title_full | Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatment |
| title_fullStr | Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatment |
| title_full_unstemmed | Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatment |
| title_short | Complications of microwave ablation in patients with persistent/recurrent hyperparathyroidism after surgical or ablative treatment |
| title_sort | complications of microwave ablation in patients with persistent recurrent hyperparathyroidism after surgical or ablative treatment |
| topic | Microwave ablation complication hyperparathyroidism recurrent laryngeal nerve |
| url | https://www.tandfonline.com/doi/10.1080/02656736.2024.2308063 |
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