Postmarketing safety evaluation of pemetrexed using FAERS and JADER databases

Abstract Pemetrexed, a multi-target antifolate chemotherapeutic widely used in non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM), is associated with various adverse drug events (ADEs), some of which may be underrecognized in clinical trials. This study conducted a comprehen...

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Bibliographic Details
Main Authors: Luo Lv, Xiangyang Wu, Yubo Ren, Yuli Guo, Haixiong Wang, Xiaofang Li
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-02426-9
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