A therapeutic approach to atopic eczema

Atopic eczema is a common problem in general practice. The underlying disorder is a barrier dysfunction of the skin, but exacerbations of eczema can be triggered by a range of external and internal factors. In young children, dietary factors are important triggers of exacerbations and specific IgE s...

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Main Author: Paul C. Potter
Format: Article
Language:English
Published: AOSIS 2010-08-01
Series:South African Family Practice
Subjects:
Online Access:https://safpj.co.za/index.php/safpj/article/view/1535
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author Paul C. Potter
author_facet Paul C. Potter
author_sort Paul C. Potter
collection DOAJ
description Atopic eczema is a common problem in general practice. The underlying disorder is a barrier dysfunction of the skin, but exacerbations of eczema can be triggered by a range of external and internal factors. In young children, dietary factors are important triggers of exacerbations and specific IgE sensitivity to common allergens may be confirmed by skin prick testing or ImmunoCap® RAST tests. True sensitivity to foods is best confirmed by a controlled food challenge, and cut off values have been published which indicate the predictive values of blood or skin tests for true food sensitivity to guide the clinician. Elimination of identifiable triggers, the use of emollients and topical corticosteroids remain the mainstay of treatments. Calcineurin inhibitors have a place for treatment of selected cases. The use of systemic corticosteroids is discouraged and patients who do not respond to emollients, specific food avoidance and corticosteroids topically should be referred to a dermatologist. The role of maternal diet in preventing the development of eczema in the offspring remains controversial.
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spelling doaj-art-b20ef07f14954f179a0e7aa6fb1808832025-08-20T04:03:17ZengAOSISSouth African Family Practice2078-61902078-62042010-08-0152427728210.1080/20786204.2010.108739901267A therapeutic approach to atopic eczemaPaul C. Potter0University of Cape Town Lung Institute, South Africa; and, Groote Schuur HospitalAtopic eczema is a common problem in general practice. The underlying disorder is a barrier dysfunction of the skin, but exacerbations of eczema can be triggered by a range of external and internal factors. In young children, dietary factors are important triggers of exacerbations and specific IgE sensitivity to common allergens may be confirmed by skin prick testing or ImmunoCap® RAST tests. True sensitivity to foods is best confirmed by a controlled food challenge, and cut off values have been published which indicate the predictive values of blood or skin tests for true food sensitivity to guide the clinician. Elimination of identifiable triggers, the use of emollients and topical corticosteroids remain the mainstay of treatments. Calcineurin inhibitors have a place for treatment of selected cases. The use of systemic corticosteroids is discouraged and patients who do not respond to emollients, specific food avoidance and corticosteroids topically should be referred to a dermatologist. The role of maternal diet in preventing the development of eczema in the offspring remains controversial.https://safpj.co.za/index.php/safpj/article/view/1535atopic eczemabarrier dysfunctiondietary factors
spellingShingle Paul C. Potter
A therapeutic approach to atopic eczema
South African Family Practice
atopic eczema
barrier dysfunction
dietary factors
title A therapeutic approach to atopic eczema
title_full A therapeutic approach to atopic eczema
title_fullStr A therapeutic approach to atopic eczema
title_full_unstemmed A therapeutic approach to atopic eczema
title_short A therapeutic approach to atopic eczema
title_sort therapeutic approach to atopic eczema
topic atopic eczema
barrier dysfunction
dietary factors
url https://safpj.co.za/index.php/safpj/article/view/1535
work_keys_str_mv AT paulcpotter atherapeuticapproachtoatopiceczema
AT paulcpotter therapeuticapproachtoatopiceczema