Hallmarks of cellular senescence: biology, mechanisms, regulations

Hallmarks of cellular senescence: biology, mechanisms, regulations

Abstract Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, telomere shortening and oxidative stress, can trigger cellular senescence. Physiologically, cellu...

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Main Authors: Amir Ajoolabady, Domenico Pratico, Suhad Bahijri, Jaakko Tuomilehto, Vladimir N. Uversky, Jun Ren
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01480-7
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