Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats

Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats

Background Hypothermic ischemia-reperfusion arrhythmia is a common complication after cardiopulmonary bypass heart surgery, which can lead to hemodynamic disorders and even sudden cardiac death and is still not effectively prevented. This study aims to investigate the role and mechanisms of EB1 in h...

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Bibliographic Details
Main Authors: Chunlei Wen, Rongfeng Yang, Jing Yi, Ying Cao, Yuting Song, Li An, Zijun Wang, Hong Gao
Format: Article
Language:English
Published: PeerJ Inc. 2025-04-01
Series:PeerJ
Subjects:
Myocardial reperfusion
Arrhythmia
Connexin 43
End-binding protein 1
Cardiac conduction
Online Access:https://peerj.com/articles/19276.pdf
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