Monoclonal Antibodies Conjugated with Superparamagnetic Iron Oxide Particles Allow Magnetic Resonance Imaging Detection of Lymphocytes in the Mouse Brain

Monoclonal Antibodies Conjugated with Superparamagnetic Iron Oxide Particles Allow Magnetic Resonance Imaging Detection of Lymphocytes in the Mouse Brain

We investigated the potential of antibody-vectorialized superparamagnetic iron oxide (SPIO) particles as cellular specific magnetic resonance contrast agents to image lymphocyte populations within the central nervous system (CNS), with the final goal of obtaining a reliable tool for noninvasively de...

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Bibliographic Details
Main Authors: Alessandro Luchetti, Davide Milani, Francesca Ruffini, Rossella Galli, Andrea Falini, Angelo Quattrini, Giuseppe Scotti, Giancarlo Comi, Gianvito Martino, Roberto Furlan, Letterio S. Politi
Format: Article
Language:English
Published: SAGE Publishing 2012-03-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2011.00032
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