Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung
Radiofrequency ablation (RFA) is a minimally invasive procedure that utilizes localized heat to treat tumors by inducing localized tissue thermal damage. The present study aimed to evaluate the temperature evolution and spatial distribution, ablation size, and reproducibility of ablation zones in ex...
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2025-01-01
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| author | Sanzhar Korganbayev Leonardo Bianchi Clara Girgi Elva Vergantino Domiziana Santucci Eliodoro Faiella Paola Saccomandi |
| author_facet | Sanzhar Korganbayev Leonardo Bianchi Clara Girgi Elva Vergantino Domiziana Santucci Eliodoro Faiella Paola Saccomandi |
| author_sort | Sanzhar Korganbayev |
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| description | Radiofrequency ablation (RFA) is a minimally invasive procedure that utilizes localized heat to treat tumors by inducing localized tissue thermal damage. The present study aimed to evaluate the temperature evolution and spatial distribution, ablation size, and reproducibility of ablation zones in ex vivo liver, kidney, and lung using a commercial device, i.e., Dophi™ R150E RFA system (Surgnova, Beijing, China), and to compare the results with the manufacturer’s specifications. Optical fibers embedding arrays of fiber Bragg grating (FBG) sensors, characterized by 0.1 °C accuracy and 1.2 mm spatial resolution, were employed for thermometry during the procedures. Experiments were conducted for all the organs in two different configurations: single-electrode (200 W for 12 min) and double-electrode (200 W for 9 min). Results demonstrated consistent and reproducible ablation zones across all organ types, with variations in temperature distribution and ablation size influenced by tissue characteristics and RFA settings. Higher temperatures were achieved in the liver; conversely, the lung exhibited the smallest ablation zone and the lowest maximum temperatures. The study found that using two electrodes for 9 min produced larger, more rounded ablation areas compared to a single electrode for 12 min. Our findings support the efficacy of the RFA system and highlight the need for tailored RFA parameters based on organ type and tumor properties. This research provides insights into the characterization of RFA systems for optimizing RFA techniques and underscores the importance of accurate thermometry and precise procedural planning to enhance clinical outcomes. |
| format | Article |
| id | doaj-art-b16211ebeef14f7a8ca3bc6b085df1a2 |
| institution | Kabale University |
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| language | English |
| publishDate | 2025-01-01 |
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| spelling | doaj-art-b16211ebeef14f7a8ca3bc6b085df1a22025-01-10T13:21:20ZengMDPI AGSensors1424-82202025-01-0125124510.3390/s25010245Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and LungSanzhar Korganbayev0Leonardo Bianchi1Clara Girgi2Elva Vergantino3Domiziana Santucci4Eliodoro Faiella5Paola Saccomandi6Department of Mechanical Engineering, Politecnico di Milano, Via Giuseppe La Masa 1, 20156 Milan, ItalyDepartment of Mechanical Engineering, Politecnico di Milano, Via Giuseppe La Masa 1, 20156 Milan, ItalyDepartment of Mechanical Engineering, Politecnico di Milano, Via Giuseppe La Masa 1, 20156 Milan, ItalyOperative Research Unit of Radiology and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, 00128 Rome, ItalyOperative Research Unit of Radiology and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, 00128 Rome, ItalyOperative Research Unit of Radiology and Interventional Radiology, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, 00128 Rome, ItalyDepartment of Mechanical Engineering, Politecnico di Milano, Via Giuseppe La Masa 1, 20156 Milan, ItalyRadiofrequency ablation (RFA) is a minimally invasive procedure that utilizes localized heat to treat tumors by inducing localized tissue thermal damage. The present study aimed to evaluate the temperature evolution and spatial distribution, ablation size, and reproducibility of ablation zones in ex vivo liver, kidney, and lung using a commercial device, i.e., Dophi™ R150E RFA system (Surgnova, Beijing, China), and to compare the results with the manufacturer’s specifications. Optical fibers embedding arrays of fiber Bragg grating (FBG) sensors, characterized by 0.1 °C accuracy and 1.2 mm spatial resolution, were employed for thermometry during the procedures. Experiments were conducted for all the organs in two different configurations: single-electrode (200 W for 12 min) and double-electrode (200 W for 9 min). Results demonstrated consistent and reproducible ablation zones across all organ types, with variations in temperature distribution and ablation size influenced by tissue characteristics and RFA settings. Higher temperatures were achieved in the liver; conversely, the lung exhibited the smallest ablation zone and the lowest maximum temperatures. The study found that using two electrodes for 9 min produced larger, more rounded ablation areas compared to a single electrode for 12 min. Our findings support the efficacy of the RFA system and highlight the need for tailored RFA parameters based on organ type and tumor properties. This research provides insights into the characterization of RFA systems for optimizing RFA techniques and underscores the importance of accurate thermometry and precise procedural planning to enhance clinical outcomes.https://www.mdpi.com/1424-8220/25/1/245fiber Bragg grating sensorsthermometryradiofrequency ablationliverkidneylung |
| spellingShingle | Sanzhar Korganbayev Leonardo Bianchi Clara Girgi Elva Vergantino Domiziana Santucci Eliodoro Faiella Paola Saccomandi Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung Sensors fiber Bragg grating sensors thermometry radiofrequency ablation liver kidney lung |
| title | Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung |
| title_full | Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung |
| title_fullStr | Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung |
| title_full_unstemmed | Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung |
| title_short | Fiber Bragg Grating Thermometry and Post-Treatment Ablation Size Analysis of Radiofrequency Thermal Ablation on Ex Vivo Liver, Kidney and Lung |
| title_sort | fiber bragg grating thermometry and post treatment ablation size analysis of radiofrequency thermal ablation on ex vivo liver kidney and lung |
| topic | fiber Bragg grating sensors thermometry radiofrequency ablation liver kidney lung |
| url | https://www.mdpi.com/1424-8220/25/1/245 |
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