TREM2-mediated regulation of microglial activity: a promising target for the treatment of ischemic stroke

Abstract Ischemic stroke, the most prevalent type of stroke globally, poses significant challenges due to its high incidence, morbidity, and long-term disability. Microglia, the resident immune cells of the central nervous system (CNS), play a dual role in the context of ischemic stroke. While they...

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Bibliographic Details
Main Authors: Haihan Yu, Li Zhang, Bo Song, Kaidi Ren, Xing Chen, Yuwan Dai, Yang Yang, Yuming Xu, Ziqing Wei
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
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Online Access:https://doi.org/10.1186/s12967-025-06799-3
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