Comprehensive bioinformatic profiling of matrix metalloproteinases and their inhibitors: Expression and interaction patterns in head and neck cancer toward predictive biomarkers and personalized therapies
Objective: Matrix metalloproteinases (MMPs) and Tissue inhibitors of metalloproteinases (TIMPs) are involved in the turnover of extracellular matrix (ECM) components. Overexpression of MMPs facilitates tumour progression by promoting ECM turnover, angiogenesis, and cell migration. Head and neck squa...
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Main Authors: | Rishaba Byju, Sredha Sunil, Sabari Sadhasivan, Rajesh Parsanathan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-09-01
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Series: | Oral Oncology Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906024004291 |
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