<i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review
Background: This systematic review aimed to synthesize the existing evidence on the use of <i>Streptococcus salivarius</i> (<i>S. salivarius</i>) probiotics as prophylactic or therapeutic tools for pediatric oral, dental, and respiratory diseases. Methods: A comprehensive sea...
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2024-12-01
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| author | Flavia Cristina Al-Akel Lacramioara Eliza Chiperi Vas Krisztina Eszter Anca Bacârea |
| author_facet | Flavia Cristina Al-Akel Lacramioara Eliza Chiperi Vas Krisztina Eszter Anca Bacârea |
| author_sort | Flavia Cristina Al-Akel |
| collection | DOAJ |
| description | Background: This systematic review aimed to synthesize the existing evidence on the use of <i>Streptococcus salivarius</i> (<i>S. salivarius</i>) probiotics as prophylactic or therapeutic tools for pediatric oral, dental, and respiratory diseases. Methods: A comprehensive search was carried out across multiple databases using the following terms: <i>S. salivarius</i>, probiotic, children, pediatric. Results: The systematic literature search identified 613 publications, which were meticulously screened, and, ultimately, 15 suitable citations were included in this systematic review. Three strains of <i>S. salivarius</i> (M18, K-12, 24SMB) were used, and they all demonstrated positive benefits in pediatric pathology. Conclusions: Administration of <i>S. salivarius</i> has benefits, is effective, and is convenient (cost-effective) in pediatric prophylaxis. Oral administration as a chewable tablet or powder of <i>S. salivarius</i> M18 for 3 months is able to reduce the incidence of black stains, plaque, and tooth decay in children. <i>S. salivarius</i> K-12 treatment decreased the occurrence of pharyngeal, recurrent, and streptococcal disease, and the benefits also extend to a reduction of nonstreptococcal diseases, including tracheitis, viral pharyngitis, rhinitis, flu, laryngitis, acute otitis media, and enteritis. Administration of <i>S. salivarius</i> 24SMB as an intranasal spray was able to reduce the risk of acute otitis media in children prone to this condition. |
| format | Article |
| id | doaj-art-b0c7e511884341b8a4ced9687ffceb2e |
| institution | Kabale University |
| issn | 2075-1729 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj-art-b0c7e511884341b8a4ced9687ffceb2e2024-12-27T14:36:05ZengMDPI AGLife2075-17292024-12-011412161310.3390/life14121613<i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic ReviewFlavia Cristina Al-Akel0Lacramioara Eliza Chiperi1Vas Krisztina Eszter2Anca Bacârea3Physiopathology Department, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, RomaniaDepartment of Pediatric Cardiology, Emergency Institute for Cardiovascular Diseases and Heart Transplant, 540136 Targu Mures, RomaniaDepartment of Laboratory Medicine, County Hospital, 530173 Miercurea Ciuc, RomaniaPhysiopathology Department, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, RomaniaBackground: This systematic review aimed to synthesize the existing evidence on the use of <i>Streptococcus salivarius</i> (<i>S. salivarius</i>) probiotics as prophylactic or therapeutic tools for pediatric oral, dental, and respiratory diseases. Methods: A comprehensive search was carried out across multiple databases using the following terms: <i>S. salivarius</i>, probiotic, children, pediatric. Results: The systematic literature search identified 613 publications, which were meticulously screened, and, ultimately, 15 suitable citations were included in this systematic review. Three strains of <i>S. salivarius</i> (M18, K-12, 24SMB) were used, and they all demonstrated positive benefits in pediatric pathology. Conclusions: Administration of <i>S. salivarius</i> has benefits, is effective, and is convenient (cost-effective) in pediatric prophylaxis. Oral administration as a chewable tablet or powder of <i>S. salivarius</i> M18 for 3 months is able to reduce the incidence of black stains, plaque, and tooth decay in children. <i>S. salivarius</i> K-12 treatment decreased the occurrence of pharyngeal, recurrent, and streptococcal disease, and the benefits also extend to a reduction of nonstreptococcal diseases, including tracheitis, viral pharyngitis, rhinitis, flu, laryngitis, acute otitis media, and enteritis. Administration of <i>S. salivarius</i> 24SMB as an intranasal spray was able to reduce the risk of acute otitis media in children prone to this condition.https://www.mdpi.com/2075-1729/14/12/1613<i>Streptococcus salivarius</i>probioticchildren<i>Streptococcus salivarius</i> M18<i>Streptococcus salivarius</i> K-12<i>Streptococcus salivarius</i> 24SMB |
| spellingShingle | Flavia Cristina Al-Akel Lacramioara Eliza Chiperi Vas Krisztina Eszter Anca Bacârea <i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review Life <i>Streptococcus salivarius</i> probiotic children <i>Streptococcus salivarius</i> M18 <i>Streptococcus salivarius</i> K-12 <i>Streptococcus salivarius</i> 24SMB |
| title | <i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review |
| title_full | <i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review |
| title_fullStr | <i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review |
| title_full_unstemmed | <i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review |
| title_short | <i>Streptococcus salivarius</i> Role as a Probiotic in Children’s Health and Disease Prophylaxis—A Systematic Review |
| title_sort | i streptococcus salivarius i role as a probiotic in children s health and disease prophylaxis a systematic review |
| topic | <i>Streptococcus salivarius</i> probiotic children <i>Streptococcus salivarius</i> M18 <i>Streptococcus salivarius</i> K-12 <i>Streptococcus salivarius</i> 24SMB |
| url | https://www.mdpi.com/2075-1729/14/12/1613 |
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