Case Report: Epstein-Barr virus negative lymphoepithelioma-like cholangiocarcinoma: a rare tumor that deserves further exploration. Report of a case with distinct genomic and clinical features

Lymphoepithelioma-like cholangiocarcinoma (LEL-CC) is a rare variant of cholangiocarcinoma characterized by undifferentiated malignant epithelial cells and a significant lymphoid infiltrate. Due to its rarity, there is currently no established treatment protocol for LEL-CC, and limited data are avai...

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Main Authors: Salvatore Corallo, Chiara Milani, Alessandro Vanoli, Anna Gallotti, Anna Pagani, Francesco Serra, Marcello Maestri, Valentina Ravetta, Angioletta Lasagna, Paolo Pedrazzoli, Francesco Agustoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1620328/full
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