YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2

YOD1 regulates oxidative damage of dopamine neurons in Parkinson's disease by deubiquitinating PKM2

Abstract Background Parkinson's disease (PD) is a common neurodegenerative movement disorder, mainly characterized by the degeneration and loss of dopaminergic neurons in the substantia nigra. Oxidative stress is considered to be a key contributor to dopaminergic neuronal degeneration, triggeri...

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Bibliographic Details
Main Authors: Xia Zhao, Jinfeng Sun, Fan Chen, Hao Tang, Yuqing Zeng, Luyao Li, Qin Yu, Linjie Chen, Muzaffar Hammad, Xiaoxia Xu, Ziyao Meng, Wei Wang, Guang Liang
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Clinical and Translational Medicine
Subjects:
oxidative stress
Parkinson's disease
PKM2
YOD1
Online Access:https://doi.org/10.1002/ctm2.70420
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