STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn’s Disease
Crohn’s disease (CD) results from dysregulated immune responses to gut microbiota in genetically susceptible individuals, affecting multiple areas of the gastrointestinal tract. Innate lymphoid cells (ILCs) are tissue-resident innate effector lymphocytes which play crucial roles in mucosal immune de...
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Main Authors: | Ying Tang, Sanda A. Tan, Atif Iqbal, Jian Li, Sarah C. Glover |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2019/9406146 |
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