Genomic analysis of global Plasmodium vivax populations reveals insights into the evolution of drug resistance

Genomic analysis of global Plasmodium vivax populations reveals insights into the evolution of drug resistance

Abstract Increasing reports of chloroquine resistance (CQR) in Plasmodium vivax endemic regions have led to several countries, including Indonesia, to adopt dihydroarteminsin-piperaquine instead. However, the molecular drivers of CQR remain unclear. Using a genome-wide approach, we perform a genomic...

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Main Authors: Gabrielle C. Ngwana-Joseph, Jody E. Phelan, Emilia Manko, Jamille G. Dombrowski, Simone da Silva Santos, Martha Suarez-Mutis, Gabriel Vélez-Tobón, Alberto Tobón Castaño, Ricardo Luiz Dantas Machado, Claudio R. F. Marinho, Debbie Nolder, François Nosten, Colin J. Sutherland, Susana Campino, Taane G. Clark
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54964-x
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