Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices
Background and purpose: Cardiac implanted electronic devices (CIED) require dose monitoring during each fraction of radiotherapy, which can be time consuming and may have delayed read-out times. This study explores the potential of Cherenkov imaging combined with scintillation dosimetry as an altern...
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| Format: | Article |
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Elsevier
2024-10-01
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| Series: | Physics and Imaging in Radiation Oncology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S240563162400112X |
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| author | Savannah M. Decker Allison L. Matous Rongxiao Zhang David J. Gladstone Evan K. Grove Benjamin B. Williams Michael Jermyn Shauna McVorran Lesley A. Jarvis |
| author_facet | Savannah M. Decker Allison L. Matous Rongxiao Zhang David J. Gladstone Evan K. Grove Benjamin B. Williams Michael Jermyn Shauna McVorran Lesley A. Jarvis |
| author_sort | Savannah M. Decker |
| collection | DOAJ |
| description | Background and purpose: Cardiac implanted electronic devices (CIED) require dose monitoring during each fraction of radiotherapy, which can be time consuming and may have delayed read-out times. This study explores the potential of Cherenkov imaging combined with scintillation dosimetry as an alternative verification system. Methods and materials: Time-gated, complementary metal–oxide–semiconductor (iCMOS) cameras were used to collect video images of anthropomorphic phantoms and patients undergoing radiation treatment near chest wall cardiac devices. Scintillator discs and optically stimulated luminescence dosimeters (OSLDs) were used for dose measurement. Accuracy of spatial delivery was assessed by overlaying predicted surface dose outlines derived from the treatment planning system (TPS) with the Cherenkov images. Dose measurements from OSLDs and scintillators were compared. Results: In phantom studies, Cherenkov images visibly indicated when dose was delivered to the CIED as compared to non-overlapping dose deliveries. Comparison with dose overlays revealed congruence at the planned position and non-congruence when the phantom was shifted from the initial position. Absolute doses derived from scintillator discs aligned well with the OSLD measurements and TPS predictions for three different positions, measuring within 10 % for in-field positions and within 5 % for out-of-field positions. For two patients with CIEDs imaged over 18 fractions, Cherenkov imaging confirmed positional accuracy for all fractions, and dose measured by scintillator discs deviated by <0.015 Gy from the OSLD measurements. Conclusions: Cherenkov imaging combined with scintillation dosimetry presents an alternative methodology for CIED monitoring with the added benefit of instantly detecting deviations, enabling timely corrective actions or proper patient triage. |
| format | Article |
| id | doaj-art-b05186da8d3c4d69a7b80ebce1f1dcb6 |
| institution | Kabale University |
| issn | 2405-6316 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Physics and Imaging in Radiation Oncology |
| spelling | doaj-art-b05186da8d3c4d69a7b80ebce1f1dcb62024-12-19T10:55:36ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162024-10-0132100642Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devicesSavannah M. Decker0Allison L. Matous1Rongxiao Zhang2David J. Gladstone3Evan K. Grove4Benjamin B. Williams5Michael Jermyn6Shauna McVorran7Lesley A. Jarvis8Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, United StatesRadiation Oncology, Dartmouth Cancer Center, Dartmouth-Health, Lebanon, NH 03765, United StatesThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States; Radiation Oncology, University of Missouri, Columbia, MO 65212, United StatesThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States; Radiation Oncology, Dartmouth Cancer Center, Dartmouth-Health, Lebanon, NH 03765, United StatesHeart and Vascular Center Dartmouth-Health, Lebanon, NH 03765, United StatesRadiation Oncology, Dartmouth Cancer Center, Dartmouth-Health, Lebanon, NH 03765, United StatesThayer School of Engineering, Dartmouth College, Hanover, NH 03755, United States; DoseOptics LLC, Lebanon, NH 03766, United StatesRadiation Oncology, Dartmouth Cancer Center, Dartmouth-Health, Lebanon, NH 03765, United StatesRadiation Oncology, Dartmouth Cancer Center, Dartmouth-Health, Lebanon, NH 03765, United States; Corresponding author.Background and purpose: Cardiac implanted electronic devices (CIED) require dose monitoring during each fraction of radiotherapy, which can be time consuming and may have delayed read-out times. This study explores the potential of Cherenkov imaging combined with scintillation dosimetry as an alternative verification system. Methods and materials: Time-gated, complementary metal–oxide–semiconductor (iCMOS) cameras were used to collect video images of anthropomorphic phantoms and patients undergoing radiation treatment near chest wall cardiac devices. Scintillator discs and optically stimulated luminescence dosimeters (OSLDs) were used for dose measurement. Accuracy of spatial delivery was assessed by overlaying predicted surface dose outlines derived from the treatment planning system (TPS) with the Cherenkov images. Dose measurements from OSLDs and scintillators were compared. Results: In phantom studies, Cherenkov images visibly indicated when dose was delivered to the CIED as compared to non-overlapping dose deliveries. Comparison with dose overlays revealed congruence at the planned position and non-congruence when the phantom was shifted from the initial position. Absolute doses derived from scintillator discs aligned well with the OSLD measurements and TPS predictions for three different positions, measuring within 10 % for in-field positions and within 5 % for out-of-field positions. For two patients with CIEDs imaged over 18 fractions, Cherenkov imaging confirmed positional accuracy for all fractions, and dose measured by scintillator discs deviated by <0.015 Gy from the OSLD measurements. Conclusions: Cherenkov imaging combined with scintillation dosimetry presents an alternative methodology for CIED monitoring with the added benefit of instantly detecting deviations, enabling timely corrective actions or proper patient triage.http://www.sciencedirect.com/science/article/pii/S240563162400112XCardiac implanted electronic devicesCherenkov imagingScintillation dosimetryBreast cancerPacemakersDefibrillators |
| spellingShingle | Savannah M. Decker Allison L. Matous Rongxiao Zhang David J. Gladstone Evan K. Grove Benjamin B. Williams Michael Jermyn Shauna McVorran Lesley A. Jarvis Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices Physics and Imaging in Radiation Oncology Cardiac implanted electronic devices Cherenkov imaging Scintillation dosimetry Breast cancer Pacemakers Defibrillators |
| title | Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices |
| title_full | Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices |
| title_fullStr | Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices |
| title_full_unstemmed | Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices |
| title_short | Cherenkov imaging combined with scintillation dosimetry provides real-time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices |
| title_sort | cherenkov imaging combined with scintillation dosimetry provides real time positional and dose monitoring for radiotherapy patients with cardiac implanted electronic devices |
| topic | Cardiac implanted electronic devices Cherenkov imaging Scintillation dosimetry Breast cancer Pacemakers Defibrillators |
| url | http://www.sciencedirect.com/science/article/pii/S240563162400112X |
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