Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report

PSMA-PET/CT has emerged as a superior diagnostic tool for prostate cancer, demonstrating enhanced accuracy over conventional imaging methods. Although sensitive for detecting local and metastatic prostate tumors, it can also identify other non-prostate PSMA positive lesions. Here, we report a rare c...

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Main Authors: Venetia A. Florou, Diane K. Reyes, Kenneth J. Pienta
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Urology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214442024002808
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author Venetia A. Florou
Diane K. Reyes
Kenneth J. Pienta
author_facet Venetia A. Florou
Diane K. Reyes
Kenneth J. Pienta
author_sort Venetia A. Florou
collection DOAJ
description PSMA-PET/CT has emerged as a superior diagnostic tool for prostate cancer, demonstrating enhanced accuracy over conventional imaging methods. Although sensitive for detecting local and metastatic prostate tumors, it can also identify other non-prostate PSMA positive lesions. Here, we report a rare case of a 67-year-old patient with metastatic prostate adenocarcinoma who was found to have an incidental Gastrointestinal Stromal Tumor (GIST), during restaging with 68Ga-PSMA-11 PET/CT. Given the broad application of PSMA PET/CT in prostate cancer, its role in diagnosing other non-prostate PSMA tumors remains uncertain, highlighting the need for further research into its application in cancer management.
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publishDate 2025-01-01
publisher Elsevier
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series Urology Case Reports
spelling doaj-art-b04936031e5b45638b22b1bb726509942025-01-14T04:12:23ZengElsevierUrology Case Reports2214-44202025-01-0158102926Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case reportVenetia A. Florou0Diane K. Reyes1Kenneth J. Pienta2Corresponding author.; The Cancer Ecology Center, The Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USAThe Cancer Ecology Center, The Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USAThe Cancer Ecology Center, The Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USAPSMA-PET/CT has emerged as a superior diagnostic tool for prostate cancer, demonstrating enhanced accuracy over conventional imaging methods. Although sensitive for detecting local and metastatic prostate tumors, it can also identify other non-prostate PSMA positive lesions. Here, we report a rare case of a 67-year-old patient with metastatic prostate adenocarcinoma who was found to have an incidental Gastrointestinal Stromal Tumor (GIST), during restaging with 68Ga-PSMA-11 PET/CT. Given the broad application of PSMA PET/CT in prostate cancer, its role in diagnosing other non-prostate PSMA tumors remains uncertain, highlighting the need for further research into its application in cancer management.http://www.sciencedirect.com/science/article/pii/S2214442024002808Prostate cancerPSMA-PET/CTPSMA expressionGISTIntermittent androgen deprivation therapyMetastasis
spellingShingle Venetia A. Florou
Diane K. Reyes
Kenneth J. Pienta
Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report
Urology Case Reports
Prostate cancer
PSMA-PET/CT
PSMA expression
GIST
Intermittent androgen deprivation therapy
Metastasis
title Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report
title_full Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report
title_fullStr Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report
title_full_unstemmed Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report
title_short Incidental discovery of gastrointestinal stromal tumor via PSMA-PET/CT imaging: Insights from a case report
title_sort incidental discovery of gastrointestinal stromal tumor via psma pet ct imaging insights from a case report
topic Prostate cancer
PSMA-PET/CT
PSMA expression
GIST
Intermittent androgen deprivation therapy
Metastasis
url http://www.sciencedirect.com/science/article/pii/S2214442024002808
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AT dianekreyes incidentaldiscoveryofgastrointestinalstromaltumorviapsmapetctimaginginsightsfromacasereport
AT kennethjpienta incidentaldiscoveryofgastrointestinalstromaltumorviapsmapetctimaginginsightsfromacasereport