Imaging Herpes Simplex Virus Type 1 Amplicon Vector–Mediated Gene Expression in Human Glioma Spheroids

Imaging Herpes Simplex Virus Type 1 Amplicon Vector–Mediated Gene Expression in Human Glioma Spheroids

Vectors derived from herpes simplex virus type 1 (HSV-1) have great potential for transducing therapeutic genes into the central nervous system; however, inefficient distribution of vector particles in vivo may limit their therapeutic potential in patients with gliomas. This study was performed to i...

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Bibliographic Details
Main Authors: Christine Kaestle, Alexandra Winkeler, Raphaela Richter, Heinrich Sauer, Jürgen Hescheler, Cornel Fraefel, Maria Wartenberg, Andreas H. Jacobs
Format: Article
Language:English
Published: SAGE Publishing 2011-05-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2010.00036
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