Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity
In the present study, Polyvinylalcohol/polyethyleneimine (PVA/PEI) hydrogels designed with different Glutaraldehyde (Glu) amount, PEI amount and PVA concentration were synthesized via solvent casting technique. The fabricated PVA/PEI hydrogels with different compositions we...
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| Format: | Article |
| Language: | English |
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Hitit University
2024-12-01
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| Series: | Hittite Journal of Science and Engineering |
| Online Access: | https://dergipark.org.tr/en/doi/10.17350/HJSE19030000345 |
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| author | Emel Tamahkar Irmak Bengi Özkahraman Gülşen Bayrak Işık Perçin Demirçelik Zeynep Ciğeroğlu Filiz Boran |
| author_facet | Emel Tamahkar Irmak Bengi Özkahraman Gülşen Bayrak Işık Perçin Demirçelik Zeynep Ciğeroğlu Filiz Boran |
| author_sort | Emel Tamahkar Irmak |
| collection | DOAJ |
| description |
In the present study, Polyvinylalcohol/polyethyleneimine (PVA/PEI) hydrogels designed with different Glutaraldehyde (Glu) amount, PEI amount and PVA concentration were synthesized via solvent casting technique. The fabricated PVA/PEI hydrogels with different compositions were evaluated for swelling rate, dehydration properties and antibacterial activity to determine superior combination. The swelling tests were performed for 0-300 min at pH 7.4 and 37 °C. All of the prepared PVA/PEI hydrogels swelling ratio were observed in the range of 221-321%. The highest dehydration rate was found for the PVA/PEI hydrogel with the lowest PVA concentration and the lowest dehydration rate was found for the PVA/PEI hydrogel with the highest Glu amount. All the PVA/PEI hydrogels demonstrated high antibacterial activity against E.coli. PP5 (prepared with 5% PVA, 0.5 mL PEI and 30 µL Glu) was determined as the selected hydrogels with optimized characteristics in respect to swelling, dehydration and antibacterial activity data. This study highlights potential usage of the resultant PVA/PEI hydrogels as antibacterial wound dressings in wound care applications. |
| format | Article |
| id | doaj-art-b0217aefe21d4aa9bf19a9f99bf12fe8 |
| institution | Kabale University |
| issn | 2148-4171 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Hitit University |
| record_format | Article |
| series | Hittite Journal of Science and Engineering |
| spelling | doaj-art-b0217aefe21d4aa9bf19a9f99bf12fe82025-01-12T07:13:56ZengHitit UniversityHittite Journal of Science and Engineering2148-41712024-12-0111418118910.17350/HJSE19030000345 Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity Emel Tamahkar Irmak0https://orcid.org/0000-0002-5913-8333Bengi Özkahraman1https://orcid.org/0000-0003-1535-4381Gülşen Bayrak2https://orcid.org/0000-0003-4567-8053Işık Perçin Demirçelik3https://orcid.org/0000-0002-9453-4462Zeynep Ciğeroğlu4https://orcid.org/0000-0001-5625-6222Filiz Boran5https://orcid.org/0000-0002-4315-9949BURSA TEKNİK ÜNİVERSİTESİHİTİT ÜNİVERSİTESİHACETTEPE ÜNİVERSİTESİHACETTEPE ÜNİVERSİTESİUŞAK ÜNİVERSİTESİHİTİT ÜNİVERSİTESİ In the present study, Polyvinylalcohol/polyethyleneimine (PVA/PEI) hydrogels designed with different Glutaraldehyde (Glu) amount, PEI amount and PVA concentration were synthesized via solvent casting technique. The fabricated PVA/PEI hydrogels with different compositions were evaluated for swelling rate, dehydration properties and antibacterial activity to determine superior combination. The swelling tests were performed for 0-300 min at pH 7.4 and 37 °C. All of the prepared PVA/PEI hydrogels swelling ratio were observed in the range of 221-321%. The highest dehydration rate was found for the PVA/PEI hydrogel with the lowest PVA concentration and the lowest dehydration rate was found for the PVA/PEI hydrogel with the highest Glu amount. All the PVA/PEI hydrogels demonstrated high antibacterial activity against E.coli. PP5 (prepared with 5% PVA, 0.5 mL PEI and 30 µL Glu) was determined as the selected hydrogels with optimized characteristics in respect to swelling, dehydration and antibacterial activity data. This study highlights potential usage of the resultant PVA/PEI hydrogels as antibacterial wound dressings in wound care applications.https://dergipark.org.tr/en/doi/10.17350/HJSE19030000345 |
| spellingShingle | Emel Tamahkar Irmak Bengi Özkahraman Gülşen Bayrak Işık Perçin Demirçelik Zeynep Ciğeroğlu Filiz Boran Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity Hittite Journal of Science and Engineering |
| title |
Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity
|
| title_full |
Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity
|
| title_fullStr |
Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity
|
| title_full_unstemmed |
Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity
|
| title_short |
Polyvinylalcohol/Polyethyleneimine Hydrogels: Evaluation of Swelling, Dehydration and Antibacterial Activity
|
| title_sort | polyvinylalcohol polyethyleneimine hydrogels evaluation of swelling dehydration and antibacterial activity |
| url | https://dergipark.org.tr/en/doi/10.17350/HJSE19030000345 |
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