Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report
Abstract Background Metastasis of malignant tumors to the cardiac endocardium is rare and mainly involves the right side of the heart. It is extremely rare to involve the left cardiac endocardium, especially when there is neither pulmonary metastasis nor primary lung cancer, which we call “isolated”...
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BMC
2024-11-01
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| Series: | World Journal of Surgical Oncology |
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| Online Access: | https://doi.org/10.1186/s12957-024-03603-2 |
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| author | Lanyue Huang Yanhui Li Rui Li Houjuan Zuo Daowen Wang Hesong Zeng Peng Deng Ligang Liu Xiang Wei Jingqun Zhang |
| author_facet | Lanyue Huang Yanhui Li Rui Li Houjuan Zuo Daowen Wang Hesong Zeng Peng Deng Ligang Liu Xiang Wei Jingqun Zhang |
| author_sort | Lanyue Huang |
| collection | DOAJ |
| description | Abstract Background Metastasis of malignant tumors to the cardiac endocardium is rare and mainly involves the right side of the heart. It is extremely rare to involve the left cardiac endocardium, especially when there is neither pulmonary metastasis nor primary lung cancer, which we call “isolated” left cardiac endocardium metastasis in this paper. Few such cases previously reported in the literature were not screened for patent foramen ovale (PFO). Case presentation This article reports a case of a young woman with a history of surgery for cervical cancer, who was transferred to our hospital with a suspected diagnosis of PFO after recent recurrent multiple cerebral infarctions. On admission, transthoracic echocardiography revealed multiple stringy vegetations in the left ventricle, which were subsequently removed surgically, with intraoperative confirmation of a patent foramen ovale and closure of it simultaneously. According to her medical history and pathological results, she was diagnosed with left ventricular metastasis of cervical cancer, a rare case of isolated left heart endocardium metastasis without previous pulmonary metastasis, presumably through the patent foramen ovale. Conclusion PFO may play an important role in the process of isolated left heart endocardium metastasis in patients with distant malignancies and paradoxical embolism. Screening for PFO in high-risk patients may have significant clinical significance. |
| format | Article |
| id | doaj-art-af79d35675b04b53b04257f7b29a34ed |
| institution | Kabale University |
| issn | 1477-7819 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj-art-af79d35675b04b53b04257f7b29a34ed2024-12-01T12:28:55ZengBMCWorld Journal of Surgical Oncology1477-78192024-11-012211610.1186/s12957-024-03603-2Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case reportLanyue Huang0Yanhui Li1Rui Li2Houjuan Zuo3Daowen Wang4Hesong Zeng5Peng Deng6Ligang Liu7Xiang Wei8Jingqun Zhang9Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiothoracic and Vascular Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDivision of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyAbstract Background Metastasis of malignant tumors to the cardiac endocardium is rare and mainly involves the right side of the heart. It is extremely rare to involve the left cardiac endocardium, especially when there is neither pulmonary metastasis nor primary lung cancer, which we call “isolated” left cardiac endocardium metastasis in this paper. Few such cases previously reported in the literature were not screened for patent foramen ovale (PFO). Case presentation This article reports a case of a young woman with a history of surgery for cervical cancer, who was transferred to our hospital with a suspected diagnosis of PFO after recent recurrent multiple cerebral infarctions. On admission, transthoracic echocardiography revealed multiple stringy vegetations in the left ventricle, which were subsequently removed surgically, with intraoperative confirmation of a patent foramen ovale and closure of it simultaneously. According to her medical history and pathological results, she was diagnosed with left ventricular metastasis of cervical cancer, a rare case of isolated left heart endocardium metastasis without previous pulmonary metastasis, presumably through the patent foramen ovale. Conclusion PFO may play an important role in the process of isolated left heart endocardium metastasis in patients with distant malignancies and paradoxical embolism. Screening for PFO in high-risk patients may have significant clinical significance.https://doi.org/10.1186/s12957-024-03603-2Patent foramen ovale (PFO)Cervical cancerMalignant tumorsMetastasisLeft ventricle |
| spellingShingle | Lanyue Huang Yanhui Li Rui Li Houjuan Zuo Daowen Wang Hesong Zeng Peng Deng Ligang Liu Xiang Wei Jingqun Zhang Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report World Journal of Surgical Oncology Patent foramen ovale (PFO) Cervical cancer Malignant tumors Metastasis Left ventricle |
| title | Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report |
| title_full | Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report |
| title_fullStr | Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report |
| title_full_unstemmed | Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report |
| title_short | Cervical cancer with patent foramen ovale metastasis to the left ventricle: a case report |
| title_sort | cervical cancer with patent foramen ovale metastasis to the left ventricle a case report |
| topic | Patent foramen ovale (PFO) Cervical cancer Malignant tumors Metastasis Left ventricle |
| url | https://doi.org/10.1186/s12957-024-03603-2 |
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