Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity

Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity

Abstract Background Drug resistance and immune escape continue to contribute to poor prognosis in AML. Increasing evidence suggests that exosomes play a crucial role in AML immune microenvironment. Methods Sanger sequencing, RNase R and fluorescence in situ hybridization were performed to confirm th...

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Bibliographic Details
Main Authors: Can Can, Xinyu Yang, Hexiao Jia, Hanyang Wu, Xiaodong Guo, Yihong Wei, Ziting Jia, Wancheng Liu, Amin Zhang, Na He, Hailei Zhang, Daoxin Ma
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Cancer
Subjects:
Acute myeloid leukemia
CircRNAs
Exosome
Arachidonic acid metabolism
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12943-024-02203-8
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