Structure-mutagenicity relationships on quinoline and indole analogues in the Ames test

Abstract Background Although the in silico predictive ability of the Ames test results has recently made remarkable progress, there are still some chemical classes for which the predictive ability is not yet sufficient due to a lack of Ames test data. These classes include simple heterocyclic compou...

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Bibliographic Details
Main Authors: Masaki Kurakami, Atsushi Hakura, Rika Sato, Akihiro Kawade, Takeshi Yamagata, Naoki Koyama, Dai Kakiuchi, Shoji Asakura
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Genes and Environment
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Online Access:https://doi.org/10.1186/s41021-024-00316-6
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