Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report
Abstracts: Objective: Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare type of endometrial cancer with limited research and understanding. This report presents a case of PESCC and reviews 37 cases from 1997. Case report: A 61-year-old menopausal woman presented with abnormal...
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Elsevier
2025-01-01
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Series: | Taiwanese Journal of Obstetrics & Gynecology |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455924002961 |
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author | Kuang-Han Liu Chia-Chin Tsai Krystal Baysan Lin Pei-Shen Huang |
author_facet | Kuang-Han Liu Chia-Chin Tsai Krystal Baysan Lin Pei-Shen Huang |
author_sort | Kuang-Han Liu |
collection | DOAJ |
description | Abstracts: Objective: Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare type of endometrial cancer with limited research and understanding. This report presents a case of PESCC and reviews 37 cases from 1997. Case report: A 61-year-old menopausal woman presented with abnormal vaginal bleeding. Despite no prior Papanicolaou smears and normal Pap results this time, transvaginal sonography revealed 7 mm endometrial thickening and elevated cancer antigen 125 (CA-125). Dilatation and curettage revealed atypical glands with squamous metaplasia. On May 3, 2017, she underwent robot-assisted staging surgery (stage IB) and pelvic radiotherapy. No disease recurrence observed till now. Conclusion: Early diagnosis of PESCC is crucial for management. Although guidelines are lacking due to the rarity of PESCC, increased reporting and research are expected to shed light on this condition and facilitate the establishment of treatment protocols. |
format | Article |
id | doaj-art-ae50b5d1b3d3490f872c746004a9eba8 |
institution | Kabale University |
issn | 1028-4559 |
language | English |
publishDate | 2025-01-01 |
publisher | Elsevier |
record_format | Article |
series | Taiwanese Journal of Obstetrics & Gynecology |
spelling | doaj-art-ae50b5d1b3d3490f872c746004a9eba82025-01-09T06:12:54ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592025-01-01641159165Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case reportKuang-Han Liu0Chia-Chin Tsai1Krystal Baysan Lin2Pei-Shen Huang3Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Pathology, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, College of Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author. No.252, Wuxing St., Xinyi Dist., Taipei City 110, Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan.Abstracts: Objective: Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare type of endometrial cancer with limited research and understanding. This report presents a case of PESCC and reviews 37 cases from 1997. Case report: A 61-year-old menopausal woman presented with abnormal vaginal bleeding. Despite no prior Papanicolaou smears and normal Pap results this time, transvaginal sonography revealed 7 mm endometrial thickening and elevated cancer antigen 125 (CA-125). Dilatation and curettage revealed atypical glands with squamous metaplasia. On May 3, 2017, she underwent robot-assisted staging surgery (stage IB) and pelvic radiotherapy. No disease recurrence observed till now. Conclusion: Early diagnosis of PESCC is crucial for management. Although guidelines are lacking due to the rarity of PESCC, increased reporting and research are expected to shed light on this condition and facilitate the establishment of treatment protocols.http://www.sciencedirect.com/science/article/pii/S1028455924002961Primary endometrial squamous cell carcinoma(PESCC)Squamous cell carcinomaDilatation and curettageHysteroscopyHPV infection |
spellingShingle | Kuang-Han Liu Chia-Chin Tsai Krystal Baysan Lin Pei-Shen Huang Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report Taiwanese Journal of Obstetrics & Gynecology Primary endometrial squamous cell carcinoma(PESCC) Squamous cell carcinoma Dilatation and curettage Hysteroscopy HPV infection |
title | Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report |
title_full | Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report |
title_fullStr | Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report |
title_full_unstemmed | Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report |
title_short | Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report |
title_sort | primary endometrial squamous cell carcinoma pescc review of the literature and case report |
topic | Primary endometrial squamous cell carcinoma(PESCC) Squamous cell carcinoma Dilatation and curettage Hysteroscopy HPV infection |
url | http://www.sciencedirect.com/science/article/pii/S1028455924002961 |
work_keys_str_mv | AT kuanghanliu primaryendometrialsquamouscellcarcinomapesccreviewoftheliteratureandcasereport AT chiachintsai primaryendometrialsquamouscellcarcinomapesccreviewoftheliteratureandcasereport AT krystalbaysanlin primaryendometrialsquamouscellcarcinomapesccreviewoftheliteratureandcasereport AT peishenhuang primaryendometrialsquamouscellcarcinomapesccreviewoftheliteratureandcasereport |