Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report

Abstracts: Objective: Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare type of endometrial cancer with limited research and understanding. This report presents a case of PESCC and reviews 37 cases from 1997. Case report: A 61-year-old menopausal woman presented with abnormal...

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Main Authors: Kuang-Han Liu, Chia-Chin Tsai, Krystal Baysan Lin, Pei-Shen Huang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Taiwanese Journal of Obstetrics & Gynecology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1028455924002961
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author Kuang-Han Liu
Chia-Chin Tsai
Krystal Baysan Lin
Pei-Shen Huang
author_facet Kuang-Han Liu
Chia-Chin Tsai
Krystal Baysan Lin
Pei-Shen Huang
author_sort Kuang-Han Liu
collection DOAJ
description Abstracts: Objective: Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare type of endometrial cancer with limited research and understanding. This report presents a case of PESCC and reviews 37 cases from 1997. Case report: A 61-year-old menopausal woman presented with abnormal vaginal bleeding. Despite no prior Papanicolaou smears and normal Pap results this time, transvaginal sonography revealed 7 mm endometrial thickening and elevated cancer antigen 125 (CA-125). Dilatation and curettage revealed atypical glands with squamous metaplasia. On May 3, 2017, she underwent robot-assisted staging surgery (stage IB) and pelvic radiotherapy. No disease recurrence observed till now. Conclusion: Early diagnosis of PESCC is crucial for management. Although guidelines are lacking due to the rarity of PESCC, increased reporting and research are expected to shed light on this condition and facilitate the establishment of treatment protocols.
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id doaj-art-ae50b5d1b3d3490f872c746004a9eba8
institution Kabale University
issn 1028-4559
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Taiwanese Journal of Obstetrics & Gynecology
spelling doaj-art-ae50b5d1b3d3490f872c746004a9eba82025-01-09T06:12:54ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592025-01-01641159165Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case reportKuang-Han Liu0Chia-Chin Tsai1Krystal Baysan Lin2Pei-Shen Huang3Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Pathology, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, College of Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author. No.252, Wuxing St., Xinyi Dist., Taipei City 110, Department of Obstetrics and Gynecology, Taipei Medical University Hospital, Taipei, Taiwan.Abstracts: Objective: Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare type of endometrial cancer with limited research and understanding. This report presents a case of PESCC and reviews 37 cases from 1997. Case report: A 61-year-old menopausal woman presented with abnormal vaginal bleeding. Despite no prior Papanicolaou smears and normal Pap results this time, transvaginal sonography revealed 7 mm endometrial thickening and elevated cancer antigen 125 (CA-125). Dilatation and curettage revealed atypical glands with squamous metaplasia. On May 3, 2017, she underwent robot-assisted staging surgery (stage IB) and pelvic radiotherapy. No disease recurrence observed till now. Conclusion: Early diagnosis of PESCC is crucial for management. Although guidelines are lacking due to the rarity of PESCC, increased reporting and research are expected to shed light on this condition and facilitate the establishment of treatment protocols.http://www.sciencedirect.com/science/article/pii/S1028455924002961Primary endometrial squamous cell carcinoma(PESCC)Squamous cell carcinomaDilatation and curettageHysteroscopyHPV infection
spellingShingle Kuang-Han Liu
Chia-Chin Tsai
Krystal Baysan Lin
Pei-Shen Huang
Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report
Taiwanese Journal of Obstetrics & Gynecology
Primary endometrial squamous cell carcinoma(PESCC)
Squamous cell carcinoma
Dilatation and curettage
Hysteroscopy
HPV infection
title Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report
title_full Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report
title_fullStr Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report
title_full_unstemmed Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report
title_short Primary endometrial squamous cell carcinoma (PESCC): Review of the literature and case report
title_sort primary endometrial squamous cell carcinoma pescc review of the literature and case report
topic Primary endometrial squamous cell carcinoma(PESCC)
Squamous cell carcinoma
Dilatation and curettage
Hysteroscopy
HPV infection
url http://www.sciencedirect.com/science/article/pii/S1028455924002961
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AT chiachintsai primaryendometrialsquamouscellcarcinomapesccreviewoftheliteratureandcasereport
AT krystalbaysanlin primaryendometrialsquamouscellcarcinomapesccreviewoftheliteratureandcasereport
AT peishenhuang primaryendometrialsquamouscellcarcinomapesccreviewoftheliteratureandcasereport