Hypocretin: a promising target for the regulation of homeostasis

Hypocretin: a promising target for the regulation of homeostasis

Hypocretin, also known as orexin, is a hypothalamic neuropeptide that regulates essential physiological processes including arousal, energy metabolism, feeding behavior, and emotional states. Through widespread projections and two G-protein-coupled receptors—HCRT-1R and HCRT-2R—the hypocretin system...

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Bibliographic Details
Main Authors: Yutong Wang, Su Fu, Jian Mao, Kun Cui, Hong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Neuroscience
Subjects:
hypocretin (orexin)
sleep
wakefulness
metabolism
mood disorders
narcolepsy
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1638270/full
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