Burden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021
Abstract Background Maternal septicemia and other maternal infections (MSMIs) continue to pose considerable challenges to public health on a global scale. However, comprehensive data on their impacts and trends are limited, particularly in BRICS countries, which include Brazil, Russian Federation, I...
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2025-05-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | https://doi.org/10.1186/s12884-025-07694-x |
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| author | Jiao Long Qi Zhang Chao Ma |
| author_facet | Jiao Long Qi Zhang Chao Ma |
| author_sort | Jiao Long |
| collection | DOAJ |
| description | Abstract Background Maternal septicemia and other maternal infections (MSMIs) continue to pose considerable challenges to public health on a global scale. However, comprehensive data on their impacts and trends are limited, particularly in BRICS countries, which include Brazil, Russian Federation, India, China, and South Africa. This study aims to compare the global epidemiological trends of MSMIs from 1990 to 2021 to MSMIs trends in BRICS countries and examine the relationship of disease burden with age and social development. Methods Using data from the Global Burden of Disease database, this study analyzed the prevalence, incidence, death, and disability-adjusted life years (DALYs) of MSMIs from 1990 to 2021 globally and in BRICS countries. Temporal trends were assessed through estimated annual percentage change (EAPC) and percentage change. Joinpoint regression analysis was employed to rigorously evaluate time trends, allowing for the calculation of annual percentage change (APC) and average annual percentage change (AAPC), with corresponding 95% confidence intervals (CI). Results In 2021, South Africa showed the highest prevalence of MSMIs (156.54 per 100,000), while the Russian Federation exhibited the highest incidence (1,001.51 per 100,000). Deaths and DALYs of MSMIs were lowered in BRICS countries compared to global averages. Between 1990 and 2019, India experienced the greatest decline in both incidence (EAPC = -2.68%) and prevalence (EAPC = -2.65%). Despite the global decline, regional variations in incidence were observed. In China, the incidence increased significantly between 2010 and 2014 (APC = 4.15%; 95% CI: 3.59–4.71%; P < 0.001). Similarly, in the Russian Federation, the incidence rose during three distinct periods: 2000–2004 (APC = 2.52%; 95% CI: 2.0–3.05%; P < 0.001), 2004–2010 (APC = 5.2%; 95% CI: 4.95–5.44%; P < 0.001), and 2010–2015 (APC = 1.79%; 95% CI: 1.46–2.12%; P < 0.001). Conclusion MSMIs remain prevalent globally, imposing a substantial disability burden, particularly in BRICS countries. While China exhibits relatively low disease burdens, South Africa faces high prevalence, and global deaths and DALYs from MSMIs remain elevated. |
| format | Article |
| id | doaj-art-ad8e9d0616f244c1be874fc5281b0bd8 |
| institution | Kabale University |
| issn | 1471-2393 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
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| series | BMC Pregnancy and Childbirth |
| spelling | doaj-art-ad8e9d0616f244c1be874fc5281b0bd82025-08-20T03:54:11ZengBMCBMC Pregnancy and Childbirth1471-23932025-05-0125111210.1186/s12884-025-07694-xBurden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021Jiao Long0Qi Zhang1Chao Ma2Department of Anesthesiology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Anesthesiology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityDepartment of Anesthesiology, The Seventh Affiliated Hospital of Sun Yat-sen UniversityAbstract Background Maternal septicemia and other maternal infections (MSMIs) continue to pose considerable challenges to public health on a global scale. However, comprehensive data on their impacts and trends are limited, particularly in BRICS countries, which include Brazil, Russian Federation, India, China, and South Africa. This study aims to compare the global epidemiological trends of MSMIs from 1990 to 2021 to MSMIs trends in BRICS countries and examine the relationship of disease burden with age and social development. Methods Using data from the Global Burden of Disease database, this study analyzed the prevalence, incidence, death, and disability-adjusted life years (DALYs) of MSMIs from 1990 to 2021 globally and in BRICS countries. Temporal trends were assessed through estimated annual percentage change (EAPC) and percentage change. Joinpoint regression analysis was employed to rigorously evaluate time trends, allowing for the calculation of annual percentage change (APC) and average annual percentage change (AAPC), with corresponding 95% confidence intervals (CI). Results In 2021, South Africa showed the highest prevalence of MSMIs (156.54 per 100,000), while the Russian Federation exhibited the highest incidence (1,001.51 per 100,000). Deaths and DALYs of MSMIs were lowered in BRICS countries compared to global averages. Between 1990 and 2019, India experienced the greatest decline in both incidence (EAPC = -2.68%) and prevalence (EAPC = -2.65%). Despite the global decline, regional variations in incidence were observed. In China, the incidence increased significantly between 2010 and 2014 (APC = 4.15%; 95% CI: 3.59–4.71%; P < 0.001). Similarly, in the Russian Federation, the incidence rose during three distinct periods: 2000–2004 (APC = 2.52%; 95% CI: 2.0–3.05%; P < 0.001), 2004–2010 (APC = 5.2%; 95% CI: 4.95–5.44%; P < 0.001), and 2010–2015 (APC = 1.79%; 95% CI: 1.46–2.12%; P < 0.001). Conclusion MSMIs remain prevalent globally, imposing a substantial disability burden, particularly in BRICS countries. While China exhibits relatively low disease burdens, South Africa faces high prevalence, and global deaths and DALYs from MSMIs remain elevated.https://doi.org/10.1186/s12884-025-07694-xMaternal septicemia and other maternal infectionsGlobal burden of diseasePrevalenceMSMIsGBD |
| spellingShingle | Jiao Long Qi Zhang Chao Ma Burden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021 BMC Pregnancy and Childbirth Maternal septicemia and other maternal infections Global burden of disease Prevalence MSMIs GBD |
| title | Burden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021 |
| title_full | Burden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021 |
| title_fullStr | Burden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021 |
| title_full_unstemmed | Burden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021 |
| title_short | Burden and trend of maternal sepsis and other maternal infections in BRICS countries from 1990 to 2021 |
| title_sort | burden and trend of maternal sepsis and other maternal infections in brics countries from 1990 to 2021 |
| topic | Maternal septicemia and other maternal infections Global burden of disease Prevalence MSMIs GBD |
| url | https://doi.org/10.1186/s12884-025-07694-x |
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