CT-based radiomics model to predict platinum sensitivity in epithelial ovarian carcinoma: a multicentre study

CT-based radiomics model to predict platinum sensitivity in epithelial ovarian carcinoma: a multicentre study

Abstract Objective Platinum resistance carries poor prognosis in epithelial ovarian carcinoma (EOC). This study aimed to assess the value of radiomics model based on contrast-enhanced CT (ceCT) in predicting response to platinum-based chemotherapy in EOC. Materials and methods Patients with histolog...

Full description

Saved in:

Bibliographic Details
Main Authors:	Mengge He, Rahul Singh, Mandi Wang, Grace Ho, Esther M. F. Wong, Keith W. H. Chiu, Anthony K. T. Leung, Ka Yu Tse, Philip P. C. Ip, Andy Hwang, Lujun Han, Elaine Y. P. Lee
Format:	Article
Language:	English
Published:	BMC 2025-07-01
Series:	Cancer Imaging
Subjects:	Epithelial ovarian carcinoma Computed tomography Radiomics Chemotherapy Platinum-Resistance
Online Access:	https://doi.org/10.1186/s40644-025-00906-9
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Deep learning based on ultrasound images to predict platinum resistance in patients with epithelial ovarian cancer
by: Chang Su, et al.
Published: (2025-05-01)

Prognostic and Predictive Value of Systemic Inflammatory Markers in Epithelial Ovarian Cancer
by: Cem İdrisoğlu, et al.
Published: (2025-02-01)

Comparative Study of Platinum(II) and Platinum(IV) Complexes with 2‐(Pyridin‐2‐ylmethylamino)acetic Acid and 4‐(Pyridin‐2‐ylmethylamino)benzoic Acid: Experimental and Theoretical Analysis
by: Stefan Richter, et al.
Published: (2025-07-01)

Efficacy of pembrolizumab in combination with bevacizumab and oral metronomic cyclophosphamide in the treatment of platinum resistant recurrent ovarian cancer: a retrospective observational study
by: Alexandra R. Steck, et al.
Published: (2025-08-01)

CDK6 protects epithelial ovarian cancer from platinum‐induced death via FOXO3 regulation
by: Alessandra Dall'Acqua, et al.
Published: (2017-08-01)

Exploring Platinum Thin Films as Electrodes for High‐Temperature and ‐Pressure Electrochemical Studies in Aqueous Systems
by: Muna Abdulaziz, et al.
Published: (2025-08-01)

Application of Radiomics in Predicting the Prognosis of Medulloblastoma in Children
by: Jiashu Chen, et al.
Published: (2025-03-01)

Catalytic activity and utilization of platinum nanoelectrocatalysts on polymeric films
by: N. A. Yashtulov, et al.
Published: (2011-08-01)

Intratumoral and peritumoral MRI-based radiomics for predicting extrapelvic peritoneal metastasis in epithelial ovarian cancer
by: Xinyi Wang, et al.
Published: (2024-11-01)

Simulation Design of PT100 Platinum Thermistor Test System
by: LI Xiaowen, et al.
Published: (2018-01-01)

Preparation of a Platinum-Coated Copper and its Adsorption Performance on Gaseous Iodine
by: Bo LI, et al.
Published: (2025-04-01)

Nonporous platinum doped titania films: synthesis, optical and photocatalytic characteristics
by: D. V. Ihnatiuk, et al.
Published: (2017-11-01)

Dealloyed nanoporous platinum films: synthesis, characterization, and hydrogen sensing properties
by: Melike Sener, et al.
Published: (2025-08-01)

Machine Learning-Driven Radiomics Analysis for Distinguishing Mucinous and Non-Mucinous Pancreatic Cystic Lesions: A Multicentric Study
by: Neus Torra-Ferrer, et al.
Published: (2025-02-01)

Тhe solid phase interaction between platinum(II) and palladium(II) tetraammines with ammonium perrhenate in the air and inert atmosphere
by: V. I. Zarazhevskiy, et al.
Published: (2010-12-01)

Nivolumab in platinum-refractory unresectable locally advanced squamous cell carcinoma of the head and neck: A case report and literature review
by: M.S. Ruban, et al.
Published: (2025-03-01)

Corrigendum: Incorporating genotype information in a precise prediction model for platinum sensitivity in epithelial ovarian cancer
by: Nai-Yi Du, et al.
Published: (2025-05-01)

Electron deficient nanoclusters of platinum and palladium on porous silicon
by: N. A. Yashtulov
Published: (2011-06-01)

Radiomics features from the peritumoral region can be associated with the epilepsy status of glioblastoma patients
by: Yeong Chul Yun, et al.
Published: (2025-08-01)

Pembrolizumab combined with lenvatinib and metronomic cyclophosphamide in platinum-resistant ovarian cancer: a case report of durable clinical response
by: Guanlin Dai, et al.
Published: (2025-08-01)

PLATINUM METAL MINERALIZATION OF THE SOUTH URALS MAGMATIC COMPLEXES: GEOLOGICAL AND GEODYNAMIC CHARACTERISTICS OF FORMATIONS, PROBLEMS OF THEIR GENESIS, AND PROSPECTS
by: I. R. Rakhimov, et al.
Published: (2021-06-01)

The efficacy and peripheral blood predictors in recurrent platinum-resistant ovarian cancer patients treated with immune checkpoint inhibitors
by: Baoyue Pan, et al.
Published: (2025-08-01)

Open-radiomics: a collection of standardized datasets and a technical protocol for reproducible radiomics machine learning pipelines
by: Khashayar Namdar, et al.
Published: (2025-08-01)

Correction: Deep learning radiomics based on multimodal imaging for distinguishing benign and malignant breast tumours
by: Guoxiu Lu, et al.
Published: (2025-06-01)

Emerging Role of Lenvatinib in Treating Platinum-Refractory Head and Neck Cancer in Resource-Limited Settings
by: Avinash Khadela, et al.

Computed tomography radiomics of intratumoral and peritumoral microenvironments for identifying the invasiveness of subcentimeter lung adenocarcinomas
by: Yu-Qiang Zuo, et al.
Published: (2025-08-01)

A study on the repeatability of radiomics parameters under repeated CT scans
by: Yi-Zhi Zhao, et al.
Published: (2025-07-01)

Tumor Small Extracellular Vesicle‐Transmitted LncRNA CATED Promotes Platinum‐Resistance in High‐Grade Serous Ovarian Cancer
by: Yi Liu, et al.
Published: (2025-08-01)

Do all patients that undergo a ‘complete’ secondary cytoreductive surgery for platinum-sensitive recurrent ovarian cancer, benefit from it?
by: Bhatt Aditi, et al.
Published: (2024-07-01)

Radiomics as a new frontier in modern rheumatology: Chest pathology visualization advances and prospects
by: T. V. Beketova, et al.
Published: (2025-03-01)

Prediction of bone oligometastases in breast cancer using models based on deep learning radiomics of PET/CT imaging
by: Guoxiu Lu, et al.
Published: (2025-08-01)

Radiomics and Radiogenomics in Differentiating Progression, Pseudoprogression, and Radiation Necrosis in Gliomas
by: Sohil Reddy, et al.
Published: (2025-07-01)

Integrative multiomics analysis reveals the subtypes and key mechanisms of platinum resistance in gastric cancer: identification of KLF9 as a promising therapeutic target
by: Pengcheng Zhang, et al.
Published: (2025-08-01)

Survival prediction in gliomas based on MRI radiomics combined with clinical factors and molecular biomarkers
by: Min Hao, et al.
Published: (2025-08-01)

Radiomics-based classification of pediatric dental trauma in periapical radiographs: a preliminary study
by: Mengtian Peng, et al.
Published: (2025-08-01)

Investigation of the interactions and electromagnetic shielding properties of graphene oxide/platinum nanoparticle composites prepared under low-dose gamma irradiation
by: Dejan Kepić, et al.
Published: (2025-07-01)

Metal-polymer platinum nanocomposites for electrochemical conversion of hydrogen fuels in chemical power sources
by: M. V. Lebedeva, et al.
Published: (2014-06-01)

Epithelial barrier dysfunction in bronchial asthma
by: R. N. Khramova, et al.
Published: (2022-09-01)

A novel radiomics model combining GTVp, GTVnd, and clinical data for chemoradiotherapy response prediction in patients with advanced NSCLC
by: Ya Li, et al.
Published: (2025-07-01)

Influence of initial platinum-based chemotherapy on levels of He-4 protein and VEGF-A in primary tumors and metastases from ovarian cancer
by: E. M. Frantsiyants, et al.
Published: (2022-01-01)