New insight into teratogenic effects of (S)-thalidomide in zebrafish embryos growing inside the chorion and subjected to electric pulses

Abstract Studies of (S)-thalidomide were conducted on zebrafish embryos subjected to electroporation processes using a square wave pulse generator. The results showed that the electroporation increases the absorption of (S)-thalidomide through the chorion into the growing embryos, which was confirme...

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Bibliographic Details
Main Authors: Anna Małkowska, Łukasz Szymański, Julita Nowakowska, Dorota Kaczorek, Agnieszka Nosal-Wiercińska, Robert Kawęcki, Ireneusz P. Grudzinski, Anna M. Nowicka
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-00641-y
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