Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study
Study aim Identifing quantitative differences in retinal and optic nerve head blood flow detected by optical coherence tomography (OCT) angiography in moderately to severely affected glaucoma eyes of primary open angle type versus normal individuals. Patients and methods Comparative noninterventiona...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-05-01
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| Series: | Journal of the Egyptian Ophthalmological Society |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ejos.ejos_86_23 |
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| author | Amr M. Sanad Mohamed M. Mahgoub Weam M. Ebeid Rabab A. Mahmoud |
| author_facet | Amr M. Sanad Mohamed M. Mahgoub Weam M. Ebeid Rabab A. Mahmoud |
| author_sort | Amr M. Sanad |
| collection | DOAJ |
| description | Study aim
Identifing quantitative differences in retinal and optic nerve head blood flow detected by optical coherence tomography (OCT) angiography in moderately to severely affected glaucoma eyes of primary open angle type versus normal individuals.
Patients and methods
Comparative noninterventional observational prospective research has been performed on 28 eyes (16 individuals). Participants went through examination and imaging protocols. Data were collected during the period from January 2020 to May 2020. The study population was split into two cohorts: the first cohort included 14 eyes of nine individuals who suffered from glaucoma of open-angle type (moderately to severely affected), and the second cohort included 14 eyes of seven normal sex-matching and age-matching individuals.
Results
We documented a reduction in the vessel density of both the optic nerve head area (P<0.001) and superficial retinal areas in glaucomatous eyes (P<0.001), and this reduction shows statistical significance.
Conclusion
Quantitative OCT angiography analysis proved affection of both peripapillary and macular vessel density in glaucoma of open-angle type, signifying the OCT angiography role in understanding the disease’s underlying etiology. |
| format | Article |
| id | doaj-art-ad1b10974b9e4ccf8ba29ece68de7a0c |
| institution | Kabale University |
| issn | 2090-0686 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Egyptian Ophthalmological Society |
| spelling | doaj-art-ad1b10974b9e4ccf8ba29ece68de7a0c2025-01-04T10:26:27ZengWolters Kluwer Medknow PublicationsJournal of the Egyptian Ophthalmological Society2090-06862024-05-01117214415010.4103/ejos.ejos_86_23Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography studyAmr M. SanadMohamed M. MahgoubWeam M. EbeidRabab A. MahmoudStudy aim Identifing quantitative differences in retinal and optic nerve head blood flow detected by optical coherence tomography (OCT) angiography in moderately to severely affected glaucoma eyes of primary open angle type versus normal individuals. Patients and methods Comparative noninterventional observational prospective research has been performed on 28 eyes (16 individuals). Participants went through examination and imaging protocols. Data were collected during the period from January 2020 to May 2020. The study population was split into two cohorts: the first cohort included 14 eyes of nine individuals who suffered from glaucoma of open-angle type (moderately to severely affected), and the second cohort included 14 eyes of seven normal sex-matching and age-matching individuals. Results We documented a reduction in the vessel density of both the optic nerve head area (P<0.001) and superficial retinal areas in glaucomatous eyes (P<0.001), and this reduction shows statistical significance. Conclusion Quantitative OCT angiography analysis proved affection of both peripapillary and macular vessel density in glaucoma of open-angle type, signifying the OCT angiography role in understanding the disease’s underlying etiology.https://journals.lww.com/10.4103/ejos.ejos_86_23macular/peripapillary blood flowoptical coherence tomography angiographyprimary open-angle glaucoma |
| spellingShingle | Amr M. Sanad Mohamed M. Mahgoub Weam M. Ebeid Rabab A. Mahmoud Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study Journal of the Egyptian Ophthalmological Society macular/peripapillary blood flow optical coherence tomography angiography primary open-angle glaucoma |
| title | Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study |
| title_full | Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study |
| title_fullStr | Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study |
| title_full_unstemmed | Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study |
| title_short | Measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals: an optical coherence tomography angiography study |
| title_sort | measurement of retinal and optic nerve head blood flow in glaucomatous individuals compared to normal individuals an optical coherence tomography angiography study |
| topic | macular/peripapillary blood flow optical coherence tomography angiography primary open-angle glaucoma |
| url | https://journals.lww.com/10.4103/ejos.ejos_86_23 |
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