The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia
Ala”a Alhowary,1 Omar Altal,2 Diab Bani Hani,1 Anas Alrusan,1 Yaser Saleh Ba Jusair,1 Rania Al-Bataineh,3 Ahmed Al Sharie,3 Abdelwahab Aleshawi3 1Department of Anesthesiology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 21110, Jordan; 2Department of Obstetrics and Gyneco...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2024-12-01
|
| Series: | Local and Regional Anesthesia |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-maternal-and-neonatal-glycemic-stress-response-in-normal-vaginal-d-peer-reviewed-fulltext-article-LRA |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846093592493293568 |
|---|---|
| author | Alhowary A Altal O Bani Hani D Alrusan A Ba Jusair YS Al-Bataineh R Al Sharie A Aleshawi A |
| author_facet | Alhowary A Altal O Bani Hani D Alrusan A Ba Jusair YS Al-Bataineh R Al Sharie A Aleshawi A |
| author_sort | Alhowary A |
| collection | DOAJ |
| description | Ala”a Alhowary,1 Omar Altal,2 Diab Bani Hani,1 Anas Alrusan,1 Yaser Saleh Ba Jusair,1 Rania Al-Bataineh,3 Ahmed Al Sharie,3 Abdelwahab Aleshawi3 1Department of Anesthesiology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 21110, Jordan; 2Department of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan; 3Faculty of Medicine, Jordan University of Science and Technology, Irbid, 21110, JordanCorrespondence: Ala”a Alhowary, Department of Anesthesiology, Faculty of Medicine, Jordan University of Science and Technology, P. O. Box: 3030, Irbid, 22110, Jordan, Tel +962791595219, Fax +962 2 7201064, Email alaacom78@yahoo.comBackground: It has been recognized that the type of anesthetic and analgesic technique and the relative pain degree may have an influence on hyperglycemic-stress response to surgery. This comparative study aimed to assess glucose levels in both mothers and infants during normal vaginal delivery. This study aimed to investigate this stress response between mothers who received parenteral analgesia versus epidural analgesia (EA) as an objective reflection for pain response.Methods: One hundred and seventeen patients participated in this prospective comparative study. They were categorized into two groups: parenteral analgesia group (who received subcutaneous morphine) and EA group. The primary outcome was to measure the difference in blood glucose level before delivery (at 3 cm cervical dilation), at full dilation, and at the third stage of labor and compare these values between both groups. The secondary outcome was to assess the factors affecting the glycemic stress response in mothers and neonates.Results: The change in maternal glucose level at full dilation and after delivery were significantly lower in the EA group. Neonatal glucose levels were not significantly different between the two groups. The change in maternal glucose level was influenced by the number of gravity and miscarriages. Neonatal glucose levels were associated with the gestational age of delivery, birth weight, and maternal glucose level at full cervical dilation.Conclusion: EA appears superior to parenteral opioids analgesia, providing better pain management and subsequent lower stress response levels for mothers during vaginal delivery. These findings highlight the importance of the choice of analgesia during labor to optimize maternal well-being. Optimizing maternal factors (such as glycemic response) and neonatal factors (such as prematurity and birth weight) may influence the stress response of the neonates.Keywords: epidural, morphine, normal vaginal delivery, glucose |
| format | Article |
| id | doaj-art-acdc5c4b4e5a4a4bbed624e3d62026bb |
| institution | Kabale University |
| issn | 1178-7112 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Local and Regional Anesthesia |
| spelling | doaj-art-acdc5c4b4e5a4a4bbed624e3d62026bb2025-01-02T17:00:45ZengDove Medical PressLocal and Regional Anesthesia1178-71122024-12-01Volume 1711712798892The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids AnalgesiaAlhowary AAltal OBani Hani DAlrusan ABa Jusair YSAl-Bataineh RAl Sharie AAleshawi AAla”a Alhowary,1 Omar Altal,2 Diab Bani Hani,1 Anas Alrusan,1 Yaser Saleh Ba Jusair,1 Rania Al-Bataineh,3 Ahmed Al Sharie,3 Abdelwahab Aleshawi3 1Department of Anesthesiology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 21110, Jordan; 2Department of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan; 3Faculty of Medicine, Jordan University of Science and Technology, Irbid, 21110, JordanCorrespondence: Ala”a Alhowary, Department of Anesthesiology, Faculty of Medicine, Jordan University of Science and Technology, P. O. Box: 3030, Irbid, 22110, Jordan, Tel +962791595219, Fax +962 2 7201064, Email alaacom78@yahoo.comBackground: It has been recognized that the type of anesthetic and analgesic technique and the relative pain degree may have an influence on hyperglycemic-stress response to surgery. This comparative study aimed to assess glucose levels in both mothers and infants during normal vaginal delivery. This study aimed to investigate this stress response between mothers who received parenteral analgesia versus epidural analgesia (EA) as an objective reflection for pain response.Methods: One hundred and seventeen patients participated in this prospective comparative study. They were categorized into two groups: parenteral analgesia group (who received subcutaneous morphine) and EA group. The primary outcome was to measure the difference in blood glucose level before delivery (at 3 cm cervical dilation), at full dilation, and at the third stage of labor and compare these values between both groups. The secondary outcome was to assess the factors affecting the glycemic stress response in mothers and neonates.Results: The change in maternal glucose level at full dilation and after delivery were significantly lower in the EA group. Neonatal glucose levels were not significantly different between the two groups. The change in maternal glucose level was influenced by the number of gravity and miscarriages. Neonatal glucose levels were associated with the gestational age of delivery, birth weight, and maternal glucose level at full cervical dilation.Conclusion: EA appears superior to parenteral opioids analgesia, providing better pain management and subsequent lower stress response levels for mothers during vaginal delivery. These findings highlight the importance of the choice of analgesia during labor to optimize maternal well-being. Optimizing maternal factors (such as glycemic response) and neonatal factors (such as prematurity and birth weight) may influence the stress response of the neonates.Keywords: epidural, morphine, normal vaginal delivery, glucosehttps://www.dovepress.com/the-maternal-and-neonatal-glycemic-stress-response-in-normal-vaginal-d-peer-reviewed-fulltext-article-LRAepiduralmorphinenormal vaginal deliveryglucose |
| spellingShingle | Alhowary A Altal O Bani Hani D Alrusan A Ba Jusair YS Al-Bataineh R Al Sharie A Aleshawi A The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia Local and Regional Anesthesia epidural morphine normal vaginal delivery glucose |
| title | The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia |
| title_full | The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia |
| title_fullStr | The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia |
| title_full_unstemmed | The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia |
| title_short | The Maternal and Neonatal Glycemic Stress Response in Normal Vaginal Delivery: A Comparative Study Between Epidural and Parenteral Opioids Analgesia |
| title_sort | maternal and neonatal glycemic stress response in normal vaginal delivery a comparative study between epidural and parenteral opioids analgesia |
| topic | epidural morphine normal vaginal delivery glucose |
| url | https://www.dovepress.com/the-maternal-and-neonatal-glycemic-stress-response-in-normal-vaginal-d-peer-reviewed-fulltext-article-LRA |
| work_keys_str_mv | AT alhowarya thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT altalo thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT banihanid thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT alrusana thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT bajusairys thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT albatainehr thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT alshariea thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT aleshawia thematernalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT alhowarya maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT altalo maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT banihanid maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT alrusana maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT bajusairys maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT albatainehr maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT alshariea maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia AT aleshawia maternalandneonatalglycemicstressresponseinnormalvaginaldeliveryacomparativestudybetweenepiduralandparenteralopioidsanalgesia |