Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applications
Microfluidic paper-based analytical devices (µPADs) have gained significant attention in analytical science and technology due to their numerous advantages over traditional analytical techniques, including cost-effectiveness, miniaturization, and sustainability. µPADs are widely used in point-of-car...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-12-01
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| Series: | Frontiers in Lab on a Chip Technologies |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/frlct.2024.1467423/full |
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| author | Prakash Aryal Charles S. Henry Charles S. Henry Charles S. Henry Charles S. Henry |
| author_facet | Prakash Aryal Charles S. Henry Charles S. Henry Charles S. Henry Charles S. Henry |
| author_sort | Prakash Aryal |
| collection | DOAJ |
| description | Microfluidic paper-based analytical devices (µPADs) have gained significant attention in analytical science and technology due to their numerous advantages over traditional analytical techniques, including cost-effectiveness, miniaturization, and sustainability. µPADs are widely used in point-of-care diagnostics, health monitoring, environmental detection, food safety, forensics, and security. Since the first report in 2007, there have been substantial advancements in their fabrication techniques, detection methods, and applications. Over the years, significant efforts and advancements have been made to improve the cost-effectiveness, manufacturing scalability, user-friendliness, and sustainability of µPADs. In this review, we explore the general trends and advancements in the fabrication, sensing methods, and applications of µPADs, highlighting key improvements and innovations. We also examine the eco-friendliness of µPADs and present real-world success stories from field studies and citizen science initiatives. Additionally, we address the challenges associated with transitioning µPADs from the lab to the field. Finally, we examine the outlook for µPADs and propose strategies to improve their usefulness in various fields. |
| format | Article |
| id | doaj-art-acd473bb19414f12b838b3d4b07b39b0 |
| institution | Kabale University |
| issn | 2813-3862 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Lab on a Chip Technologies |
| spelling | doaj-art-acd473bb19414f12b838b3d4b07b39b02024-12-20T14:01:42ZengFrontiers Media S.A.Frontiers in Lab on a Chip Technologies2813-38622024-12-01310.3389/frlct.2024.14674231467423Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applicationsPrakash Aryal0Charles S. Henry1Charles S. Henry2Charles S. Henry3Charles S. Henry4Department of Chemistry, Colorado State University, Fort Collins, CO, United StatesDepartment of Chemistry, Colorado State University, Fort Collins, CO, United StatesDepartment of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, United StatesSchool of Biomedical Engineering, Colorado State University, Fort Collins, CO, United StatesMetallurgy and Materials Science Research Institute, Chulalongkorn University, Bangkok, ThailandMicrofluidic paper-based analytical devices (µPADs) have gained significant attention in analytical science and technology due to their numerous advantages over traditional analytical techniques, including cost-effectiveness, miniaturization, and sustainability. µPADs are widely used in point-of-care diagnostics, health monitoring, environmental detection, food safety, forensics, and security. Since the first report in 2007, there have been substantial advancements in their fabrication techniques, detection methods, and applications. Over the years, significant efforts and advancements have been made to improve the cost-effectiveness, manufacturing scalability, user-friendliness, and sustainability of µPADs. In this review, we explore the general trends and advancements in the fabrication, sensing methods, and applications of µPADs, highlighting key improvements and innovations. We also examine the eco-friendliness of µPADs and present real-world success stories from field studies and citizen science initiatives. Additionally, we address the challenges associated with transitioning µPADs from the lab to the field. Finally, we examine the outlook for µPADs and propose strategies to improve their usefulness in various fields.https://www.frontiersin.org/articles/10.3389/frlct.2024.1467423/fullpaper-based microfluidicsfabrication methodsdetection techniquesapplicationspoint-of-carepoint-of-need |
| spellingShingle | Prakash Aryal Charles S. Henry Charles S. Henry Charles S. Henry Charles S. Henry Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applications Frontiers in Lab on a Chip Technologies paper-based microfluidics fabrication methods detection techniques applications point-of-care point-of-need |
| title | Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applications |
| title_full | Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applications |
| title_fullStr | Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applications |
| title_full_unstemmed | Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applications |
| title_short | Advancements and challenges in microfluidic paper-based analytical devices: design, manufacturing, sustainability, and field applications |
| title_sort | advancements and challenges in microfluidic paper based analytical devices design manufacturing sustainability and field applications |
| topic | paper-based microfluidics fabrication methods detection techniques applications point-of-care point-of-need |
| url | https://www.frontiersin.org/articles/10.3389/frlct.2024.1467423/full |
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