Untangling sporadic brain arteriovenous malformations: towards targeting the KRAS/MAPK pathway

Untangling sporadic brain arteriovenous malformations: towards targeting the KRAS/MAPK pathway

Brain arteriovenous malformations (AVMs) are vascular lesions characterized by abnormal connections between parenchymal arteries and veins, bypassing a capillary bed, and forming a nidus. Brain AVMs are consequential as they are prone to rupture and associated with significant morbidity. They can br...

Full description

Saved in:
Bibliographic Details
Main Authors: Rashad Jabarkheel, Lun Li, Maxwell Frankfurter, Daniel Y. Zhang, Avi Gajjar, Najib Muhammad, Visish M. Srinivasan, Jan-Karl Burkhardt, Mark Kahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Surgery
Subjects:
arteriovenous malformation
sporadic
KRAS
MAPK
MEK inhibitor
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2024.1504612/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items