Inter-chromosomal contacts demarcate genome topology along a spatial gradient

Inter-chromosomal contacts demarcate genome topology along a spatial gradient

Abstract Non-homologous chromosomal contacts (NHCCs) between different chromosomes participate considerably in gene and genome regulation. Due to analytical challenges, NHCCs are currently considered as singular, stochastic events, and their extent and fundamental principles across cell types remain...

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Main Authors: Milad Mokhtaridoost, Jordan J. Chalmers, Marzieh Soleimanpoor, Brandon J. McMurray, Daniella F. Lato, Son C. Nguyen, Viktoria Musienko, Joshua O. Nash, Sergio Espeso-Gil, Sameen Ahmed, Kate Delfosse, Jared W. L. Browning, A. Rasim Barutcu, Michael D. Wilson, Thomas Liehr, Adam Shlien, Samin Aref, Eric F. Joyce, Anja Weise, Philipp G. Maass
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53983-y
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https://doi.org/10.1038/s41467-024-53983-y

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