High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report
The growing popularity of soft tissue filler injections has brought attention to the associated risks, particularly vascular complications, and their treatments. This case report focuses on a 34-year-old female who developed nasal skin necrosis following hyaluronic acid (HA) filler injection for nas...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426824000629 |
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| author | Marcelo Germani Panmella Alegria Gabriela Giro Victor R.M. Munoz-Lora |
| author_facet | Marcelo Germani Panmella Alegria Gabriela Giro Victor R.M. Munoz-Lora |
| author_sort | Marcelo Germani |
| collection | DOAJ |
| description | The growing popularity of soft tissue filler injections has brought attention to the associated risks, particularly vascular complications, and their treatments. This case report focuses on a 34-year-old female who developed nasal skin necrosis following hyaluronic acid (HA) filler injection for nasolabial fold (NLF) enhancement. Despite the careful procedure, complications emerged rapidly, emphasizing the critical importance of prompt diagnosis and intervention. A total of 10,000 turbidity reducing units (TRU) of hyaluronidase (HSE) were administered in a high-dose pulsed manner, alongside hyperbaric oxygen therapy. The patient experienced a gradual but significant improvement over 60 days. This case underscores the need for constant vigilance in aesthetic medicine and the potential consequences of even minute HA amounts, exceeding zero, in causing severe vascular events. |
| format | Article |
| id | doaj-art-ac72cac9cd9c4922b28d2ba74b38d725 |
| institution | Kabale University |
| issn | 2212-4268 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-ac72cac9cd9c4922b28d2ba74b38d7252024-11-23T06:30:50ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682024-05-01143339341High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case reportMarcelo Germani0Panmella Alegria1Gabriela Giro2Victor R.M. Munoz-Lora3Department of Periodontology and Implantology, University of Guarulhos, São Paulo, BrazilPrivate Office, São Paulo, BrazilDepartment of Periodontology and Implantology, University of Guarulhos, São Paulo, BrazilDepartment of Periodontology and Implantology, University of Guarulhos, São Paulo, Brazil; Let's HOF Academy, São Paulo, Brazil; Corresponding author. Department of periodontology and implantology, University of Guarulhos, Sao Paulo, Brazil.The growing popularity of soft tissue filler injections has brought attention to the associated risks, particularly vascular complications, and their treatments. This case report focuses on a 34-year-old female who developed nasal skin necrosis following hyaluronic acid (HA) filler injection for nasolabial fold (NLF) enhancement. Despite the careful procedure, complications emerged rapidly, emphasizing the critical importance of prompt diagnosis and intervention. A total of 10,000 turbidity reducing units (TRU) of hyaluronidase (HSE) were administered in a high-dose pulsed manner, alongside hyperbaric oxygen therapy. The patient experienced a gradual but significant improvement over 60 days. This case underscores the need for constant vigilance in aesthetic medicine and the potential consequences of even minute HA amounts, exceeding zero, in causing severe vascular events.http://www.sciencedirect.com/science/article/pii/S2212426824000629Hyaluronic acidIschemiaNecrosis |
| spellingShingle | Marcelo Germani Panmella Alegria Gabriela Giro Victor R.M. Munoz-Lora High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report Journal of Oral Biology and Craniofacial Research Hyaluronic acid Ischemia Necrosis |
| title | High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report |
| title_full | High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report |
| title_fullStr | High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report |
| title_full_unstemmed | High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report |
| title_short | High-dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds: A case report |
| title_sort | high dose pulsed hyaluronidase for managing nasal skin necrosis following hyaluronic acid treatment in nasolabial folds a case report |
| topic | Hyaluronic acid Ischemia Necrosis |
| url | http://www.sciencedirect.com/science/article/pii/S2212426824000629 |
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