Combination of Metformin and Magnesium Citrate Reduces TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 Expressions in Diabetic Model Rats

Combination of Metformin and Magnesium Citrate Reduces TNF-α, NF-κB p65, IL-6, CD4, and MMP-9 Expressions in Diabetic Model Rats

BACKGROUND: Diabetes, which causes various complications, involves pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), nuclear factor kappa B p65 (NF-κB p65), interleukin-6 (IL-6), cluster of differentiation 4 (CD4), and matrix metalloproteinase-9 (MMP-9). Magnesium has demonstra...

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Bibliographic Details
Main Authors: Rachmi Fauziah Rahayu, Adi Prayitno, Bambang Purwanto, Widiastuti Soewondo, Ida Nurwati, Eti Poncorini Pamungkasari, Paramasari Dirgahayu
Format: Article
Language:English
Published: Secretariat of The Indonesian Biomedical Journal 2024-12-01
Series:Indonesian Biomedical Journal
Online Access:https://inabj.org/index.php/ibj/article/view/3360
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