Quantification and Validation of a HPLC-UV Method for Simultaneous Analysis of Nitrosoamine Impurities (NDMA, NDEA and NDIPA) in Losartan

Quantification and Validation of a HPLC-UV Method for Simultaneous Analysis of Nitrosoamine Impurities (NDMA, NDEA and NDIPA) in Losartan

Impurity profiling is an important aspect in drug therapy for its safety and efficacy. The study of impurities of sartans, the first line antihypertensive drugs, has become critical due to presence of cancer causing N-nitrosodimethylamine (NDMA), N-nitrosodiethylamine (NDEA) and N-nitrosodi...

Full description

Saved in:
Bibliographic Details
Main Authors: Santosh Patil, Rajeev Chadar, Ashok Prasad, Poonam Koppula, Santhosh Koppula
Format: Article
Language:English
Published: Krupanidhi College of Pharmacy 2021-12-01
Series:Journal of Pharmaceutical Research
Online Access:https://jopcr.com/articles/quantification-and-validation-of-a-hplc-uv-method-for-simultaneous-analysis-of-nitrosoamine-impurities-ndma-ndea-and-ndipa-in-losartan
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items