Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction
The use of inhibitors of HMG-Co-A reductase inhibitor simvastatin, atorvastatin, rosuvastatin and nanoparticulative rosuvastatin on background modeling endotoksininducing pathology, introduction of strain 603 Staphylococcusaureus leads to the development of dose-response endotelioprotectiv action, e...
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| Format: | Article |
| Language: | Russian |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2015-10-01
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| Series: | Кубанский научный медицинский вестник |
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| Online Access: | https://ksma.elpub.ru/jour/article/view/389 |
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| author | T. A. Denisuk M. V. Pokrovskii O. V. Philippova O. S. Gudyrev T. G. Pokrovskaya M. V. Korokin O. A. Osipova |
| author_facet | T. A. Denisuk M. V. Pokrovskii O. V. Philippova O. S. Gudyrev T. G. Pokrovskaya M. V. Korokin O. A. Osipova |
| author_sort | T. A. Denisuk |
| collection | DOAJ |
| description | The use of inhibitors of HMG-Co-A reductase inhibitor simvastatin, atorvastatin, rosuvastatin and nanoparticulative rosuvastatin on background modeling endotoksininducing pathology, introduction of strain 603 Staphylococcusaureus leads to the development of dose-response endotelioprotectiv action, expressed in the normalization of QED, prevent increase adrenoreactivity and exhaustion of myocardial reserve and and normalization of biochemical markers of inflammation (C-reactive protein) and the level of proinflammatory cytokines. When this is detected positive dynamics and-products of NO and expression of eNOS. |
| format | Article |
| id | doaj-art-ac0e6f0911704f84862a7fdcb543567e |
| institution | Kabale University |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| publishDate | 2015-10-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj-art-ac0e6f0911704f84862a7fdcb543567e2025-08-20T03:57:13ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442015-10-0155155389Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunctionT. A. Denisuk0M. V. Pokrovskii1O. V. Philippova2O. S. Gudyrev3T. G. Pokrovskaya4M. V. Korokin5O. A. Osipova6FSAEI VPO «BSU», SEI HPE KSMU of Russian ministry of healthFSAEI VPO «BSU», SEI HPE KSMU of Russian ministry of healthFSAEI VPO «BSU», SEI HPE KSMU of Russian ministry of healthFSAEI VPO «BSU», SEI HPE KSMU of Russian ministry of healthFSAEI VPO «BSU», SEI HPE KSMU of Russian ministry of healthFSAEI VPO «BSU», SEI HPE KSMU of Russian ministry of healthFSAEI VPO «BSU», SEI HPE KSMU of Russian ministry of healthThe use of inhibitors of HMG-Co-A reductase inhibitor simvastatin, atorvastatin, rosuvastatin and nanoparticulative rosuvastatin on background modeling endotoksininducing pathology, introduction of strain 603 Staphylococcusaureus leads to the development of dose-response endotelioprotectiv action, expressed in the normalization of QED, prevent increase adrenoreactivity and exhaustion of myocardial reserve and and normalization of biochemical markers of inflammation (C-reactive protein) and the level of proinflammatory cytokines. When this is detected positive dynamics and-products of NO and expression of eNOS.https://ksma.elpub.ru/jour/article/view/389дисфункция эндотелияингибиторы гмг-ко-а-редуктазы симвастатинаторвастатинрозу-вастатинэндотоксинendothelial dysfunctionhmg-co-a-reductase inhibitor simvastatinatorvastatinrosuvastatinendotoxin |
| spellingShingle | T. A. Denisuk M. V. Pokrovskii O. V. Philippova O. S. Gudyrev T. G. Pokrovskaya M. V. Korokin O. A. Osipova Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction Кубанский научный медицинский вестник дисфункция эндотелия ингибиторы гмг-ко-а-редуктазы симвастатин аторвастатин розу-вастатин эндотоксин endothelial dysfunction hmg-co-a-reductase inhibitor simvastatin atorvastatin rosuvastatin endotoxin |
| title | Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction |
| title_full | Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction |
| title_fullStr | Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction |
| title_full_unstemmed | Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction |
| title_short | Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction |
| title_sort | endotelioand cardioprotective effects of hmg co a reductase in endotoksininducing endotelial dysfunction |
| topic | дисфункция эндотелия ингибиторы гмг-ко-а-редуктазы симвастатин аторвастатин розу-вастатин эндотоксин endothelial dysfunction hmg-co-a-reductase inhibitor simvastatin atorvastatin rosuvastatin endotoxin |
| url | https://ksma.elpub.ru/jour/article/view/389 |
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